DEFA6 Products
(Defensin, alpha 6, Paneth Cell-Specific (DEFA6))
Categories
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel. [provided by RefSeq, Jul 2008].
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Featured DEFA6 Categories
DEFA6 Antibodies
High quality antibodies with extensive validation data.
DEFA6 ELISA Kits
Reliable ELISA kits for a wide range of species.
DEFA6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DEFA6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN947789
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (1)
Cat. No.
ABIN7002006
Quantity
20 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, WB, IP, ICC
Validations
- (1)
Cat. No.
ABIN7435730
Quantity
100 μL
Datasheet
Datasheet
Recommended DEFA6 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955308
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955309
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN1569380
Quantity
96 tests
Datasheet
Datasheet
Recommended DEFA6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351414
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7414954
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397885
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our DEFA6 products
: "Human Defensin-5 Blocks Ethanol and Colitis-Induced Dysbiosis, Tight Junction Disruption and Inflammation in Mouse Intestine." in: Scientific reports, Vol. 8, Issue 1, pp. 16241, (2018) (PubMed).: "REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation." in: Cell and tissue research, Vol. 352, Issue 3, pp. 639-46, (2013) (PubMed).
: "Macaque paneth cells express lymphoid chemokine CXCL13 and other antimicrobial peptides not previously described as expressed in intestinal crypts." in: Clinical and vaccine immunology : CVI, Vol. 20, Issue 8, pp. 1320-8, (2013) (PubMed).
: "Activation of REG family proteins in colitis." in: Scandinavian journal of gastroenterology, Vol. 46, Issue 11, pp. 1316-23, (2011) (PubMed).
Synonyms and alternative names related to DEFA6
defensin alpha 6 (DEFA6), defensin, alpha 6, Paneth cell-specific (DEFA6), defensin alpha 6 (Defa6), defensin, alpha, 6 (Defa6), DEF6, DEFA6, Defcr6, HD-6Protein level used designations for DEFA6
- defensin, alpha 6, Paneth cell-specific
- alpha-defensin 6, Paneth cell-specific
- Paneth cell-specific alpha-defensin 6
- alpha-defensin 6
- defensin-6
- defensin 6
- alpha-defensin 6/12
- alpha-defensin, 6
- cryptdin-2
- defensin related cryptdin 6
- defensin-related cryptdin-6/12
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