DEFA1/DEFA3 antibody
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- Target
- DEFA1/DEFA3 (DEFA1A3) (Defensin, alpha 1 and alpha 3, Variable Copy Number Locus (DEFA1A3))
- Reactivity
- Human
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- Antigen affinity purification
- Immunogen
- Synthetic peptide of Human DEFA1/3
- Isotype
- IgG
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- Application Notes
- ELISA:1:1000-1:2000, IHC:1:25-1:100,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- DEFA1/DEFA3 (DEFA1A3) (Defensin, alpha 1 and alpha 3, Variable Copy Number Locus (DEFA1A3))
- Alternative Name
- DEFA1/DEFA3
- Synonyms
- DEFA1 antibody, DEFA3 antibody, DEFT1P antibody, defensin alpha 1 and alpha 3, variable copy number locus antibody, DEFA1A3 antibody
- Background
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Background: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Defensin, alpha Several alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8.
Aliases: defensin, alpha 1/3
- UniProt
- P59665, P59666
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