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DDX4 Products

(DEAD Box Protein 4 (DDX4))

Categories

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a homolog of VASA proteins in Drosophila and several other species. The gene is specifically expressed in the germ cell lineage in both sexes and functions in germ cell development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].

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Featured DDX4 Categories

DDX4 Antibodies

High quality antibodies with extensive validation data.

DDX4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DDX4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, FACS, ICC
Validations
  • (4)
  • (4)
Cat. No. ABIN969084
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), IHC (fro), ICC
Validations
  • (6)
Cat. No. ABIN3044032
Quantity 100 μg
Datasheet Datasheet
Reactivity Chicken
Application WB, FACS, IHC (p), IF (p), IHC (fro)
Validations
  • (2)
  • (3)
Cat. No. ABIN701365
Quantity 100 μL
Datasheet Datasheet

Recommended DDX4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351352
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351351
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092059
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our DDX4 products

Shirzeyli, Tayyebiazar, Aliakbari, Ghasemi, Eini, Shirzeyli, Vanaki, Sobhani: "Comparison of the efficacy of bone morphogenetic protein-4 on in vitro differentiation of murine adipose and bone marrow mesenchymal stem cells into primordial germ cells." in: , Vol. 17, Issue 2, pp. 123-133, (2022) (PubMed).

Imus, Roe, Charter, Durrant, Jensen: "Transfer and detection of freshly isolated or cultured chicken (Gallus gallus) and exotic species' embryonic gonadal germ stem cells in host embryos." in: Zoological science, Vol. 31, Issue 6, pp. 360-8, (2014) (PubMed).

Guo, Gui, Tang, Lu, Gao, Cai: "Differential expression of VASA gene in ejaculated spermatozoa from normozoospermic men and patients with oligozoospermia." in: Asian journal of andrology, Vol. 9, Issue 3, pp. 339-44, (2007) (PubMed).

Chu, Liu, Nix, Wu, Ralston, Yates, Meyer: "Sperm chromatin proteomics identifies evolutionarily conserved fertility factors." in: Nature, Vol. 443, Issue 7107, pp. 101-5, (2006) (PubMed).

Abdelhaleem: "RNA helicases: regulators of differentiation." in: Clinical biochemistry, Vol. 38, Issue 6, pp. 499-503, (2005) (PubMed).

Hoet, Cohen, Kent, Rookey, Schoonbroodt, Hogan, Rem, Frans, Daukandt, Pieters, van Hegelsom, Neer, Nastri, Rondon, Leeds, Hufton, Huang, Kashin, Devlin, Kuang, Steukers, Viswanathan, Nixon, Sexton et al.: "Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity. ..." in: Nature biotechnology, Vol. 23, Issue 3, pp. 344-8, (2005) (PubMed).

Clark, Bodnar, Fox, Rodriquez, Abeyta, Firpo, Pera: "Spontaneous differentiation of germ cells from human embryonic stem cells in vitro." in: Human molecular genetics, Vol. 13, Issue 7, pp. 727-39, (2004) (PubMed).

Shibata, Tsunekawa, Okamoto-Ito, Akasu, Tokumasu, Noce: "Mouse RanBPM is a partner gene to a germline specific RNA helicase, mouse vasa homolog protein." in: Molecular reproduction and development, Vol. 67, Issue 1, pp. 1-7, (2003) (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).

Zeeman, Stoop, Boter, Gillis, Castrillon, Oosterhuis, Looijenga: "VASA is a specific marker for both normal and malignant human germ cells." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 82, Issue 2, pp. 159-66, (2002) (PubMed).

Synonyms and alternative names related to DDX4

DEAD-box helicase 4 (DDX4), DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 (Ddx4), DEAD-box helicase 4 (Ddx4), DEAD-box helicase 4 L homeolog (ddx4.L), AV206478, Mvh, RVLG, VASA, vasa, vlg1

Protein level used designations for DDX4

  • DEAD box protein 4
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4
  • probable ATP-dependent RNA helicase DDX4
  • vasa homolog
  • D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 4
  • DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 4
  • DEAD box polypeptide 4
  • mvh / m'vasa
  • Cvh
  • vasa-like protein
  • putative ATP-dependent RNA helicase DDX4
  • vasa-like gene protein
  • xVLG1
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