DDX39B Products
(DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B))
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This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2) gene. [provided by RefSeq, Feb 2011].
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Featured DDX39B Categories
DDX39B Antibodies
High quality antibodies with extensive validation data.
DDX39B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DDX39B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, WB, ICC
Validations
- (7)
Cat. No.
ABIN5542645
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (8)
Cat. No.
ABIN7264385
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (7)
Cat. No.
ABIN2855057
Quantity
100 μL
Datasheet
Datasheet
Recommended DDX39B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122607
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
- (1)
Cat. No.
ABIN1047670
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2715156
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our DDX39B products
: "The BAT1 gene in the MHC encodes an evolutionarily conserved putative nuclear RNA helicase of the DEAD family." in: Genomics, Vol. 26, Issue 2, pp. 210-8, (1995) (PubMed).: "ALS Associated Mutations in Matrin 3 Alter Protein-Protein Interactions and Impede mRNA Nuclear Export." in: Scientific reports, Vol. 7, Issue 1, pp. 14529 (PubMed).
Synonyms and alternative names related to DDX39B
DExD-box helicase 39B (DDX39B), DExD-box helicase 39B (Ddx39b), DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (Ddx39b), DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (ddx39b), 0610030D10Rik, AI428441, Bat-1, BAT1, Bat1, bat1, Bat1a, D6S81E, D6S81Eh, D17H6S81E, D17H6S81E-1, p47, UAP56, zgc:63773Protein level used designations for DDX39B
- 56 kDa U2AF65-associated protein
- ATP-dependent RNA helicase p47
- HLA-B-associated transcript 1 protein
- nuclear RNA helicase (DEAD family)
- spliceosome RNA helicase BAT1
- spliceosome RNA helicase DDX39B
- D17H6S81E-1
- D20H6S81e
- DEAD box protein UAP56
- HLA-B associated transcript 1
- HLA-B associated transcript 1A
- HLA-B-associated transcript 1A
- Nuclear RNA helicase
- spliceosome RNA helicase Bat1
- spliceosome RNA helicase Ddx39b
- DEADD box protein
- nuclear RNA helicase Bat1
- DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
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