DCLRE1C Products
(DNA Cross-Link Repair 1C (DCLRE1C))
Categories
This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity\; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA). [provided by RefSeq, Jul 2008].
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Featured DCLRE1C Categories
DCLRE1C Antibodies
High quality antibodies with extensive validation data.
DCLRE1C Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DCLRE1C Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6261238
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN653693
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN129558
Quantity
100 μg
Datasheet
Datasheet
Recommended DCLRE1C ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6212692
Quantity
96 tests
Datasheet
Datasheet
Recommended DCLRE1C Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351199
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351198
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3092074
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our DCLRE1C products
: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).: "Defective DNA double-strand break repair in pediatric systemic lupus erythematosus." in: Arthritis and rheumatism, Vol. 64, Issue 2, pp. 568-78, (2012) (PubMed).
: "Functional and biochemical dissection of the structure-specific nuclease ARTEMIS." in: The EMBO journal, Vol. 23, Issue 9, pp. 1987-97, (2004) (PubMed).
: "Phosphorylation of Artemis following irradiation-induced DNA damage." in: European journal of immunology, Vol. 34, Issue 11, pp. 3146-55, (2004) (PubMed).
: "The metallo-beta-lactamase/beta-CASP domain of Artemis constitutes the catalytic core for V(D)J recombination." in: The Journal of experimental medicine, Vol. 199, Issue 3, pp. 315-21, (2004) (PubMed).
: "A biochemically defined system for mammalian nonhomologous DNA end joining." in: Molecular cell, Vol. 16, Issue 5, pp. 701-13, (2004) (PubMed).
: "Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination." in: Cell, Vol. 108, Issue 6, pp. 781-94, (2002) (PubMed).
: "Metallo-beta-lactamase fold within nucleic acids processing enzymes: the beta-CASP family." in: Nucleic acids research, Vol. 30, Issue 16, pp. 3592-601, (2002) (PubMed).
: "Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency." in: Cell, Vol. 105, Issue 2, pp. 177-86, (2001) (PubMed).
Synonyms and alternative names related to DCLRE1C
DNA cross-link repair 1C (DCLRE1C), DNA cross-link repair 1C (Dclre1c), 9930121L06Rik, A-SCID, AI661365, Art, artemis, DCLREC1C, hSNM1C, nuclease, RS-SCID, SCIDA, SNM1C, Snm1lProtein level used designations for DCLRE1C
- DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae)
- artemis protein
- protein artemis
- DNA cross-link repair 1C
- protein artemis-like
- DNA cross-link repair 1C protein
- PSO2 homolog
- SNM1 homolog C
- SNM1-like protein
- severe combined immunodeficiency, type a (Athabascan)
- chSNM1C
- Artemis protein
- DNA cross-link repair 1A, PSO2 homolog
- artemis
- mArt
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