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DBN1 Products

(Drebrin 1 (DBN1))
The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Featured DBN1 Categories

DBN1 Antibodies

High quality antibodies with extensive validation data.

DBN1 ELISA Kits

Reliable ELISA kits for a wide range of species.

DBN1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DBN1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, StM
Validations
  • (5)
Cat. No. ABIN6939227
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application FACS
Validations
  • (1)
  • (3)
Cat. No. ABIN1558085
Quantity 100 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6261368
Quantity 100 μL
Datasheet Datasheet

Recommended DBN1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955457
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN5608558
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN425627
Quantity 96 tests
Datasheet Datasheet

Recommended DBN1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1351156
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122708
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7396349
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our DBN1 products

Richter, Wildhagen, Helm, Ußling, Schikorski, Rizzoli: "Comparative synaptosome imaging: a semi-quantitative method to obtain copy numbers for synaptic and neuronal proteins." in: Scientific reports, Vol. 8, Issue 1, pp. 14838, (2018) (PubMed).

Bhat, Thirumangalakudi: "Increased tau phosphorylation and impaired brain insulin/IGF signaling in mice fed a high fat/high cholesterol diet." in: Journal of Alzheimer's disease : JAD, Vol. 36, Issue 4, pp. 781-9, (2013) (PubMed).

Vaskova, Kovac, Volna, Angelisova, Mejstrikova, Zuna, Brdicka, Hrusak: "High expression of cytoskeletal protein drebrin in TEL/AML1pos B-cell precursor acute lymphoblastic leukemia identified by a novel monoclonal antibody." in: Leukemia research, Vol. 35, Issue 8, pp. 1111-3, (2011) (PubMed).

Chen, Prior, Dargusch, Roberts, Riek, Eichmann, Chiruta, Akaishi, Abe, Maher, Schubert: "A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease." in: PLoS ONE, Vol. 6, Issue 12, pp. e27865, (2011) (PubMed).

Park, Yamada, Kojo, Sato, Onozuka, Yamamoto: "Drebrin (developmentally regulated brain protein) is associated with axo-somatic synapses and neuronal gap junctions in rat mesencephalic trigeminal nucleus." in: Neuroscience letters, Vol. 461, Issue 2, pp. 95-9, (2009) (PubMed).

Maezawa, Nivison, Montine, Maeda, Montine: "Neurotoxicity from innate immune response is greatest with targeted replacement of E4 allele of apolipoprotein E gene and is mediated by microglial p38MAPK." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 6, pp. 797-9, (2006) (PubMed).

Ganong, Kramer, Salmon, Reid, Lovinger, Scapagnini, Boryczka, Shackelford: "Pharmacological evidence for inhibition of ACTH secretion by a central adrenergic system in the dog." in: Neuroscience, Vol. 1, Issue 3, pp. 167-74, (2001) (PubMed).

Synonyms and alternative names related to DBN1

drebrin 1 (DBN1), drebrin 1 (Dbn1), drebrin 1 S homeolog (dbn1.S), drebrin 1 (dbn1), D0S117E, DBN1, LOC733967

Protein level used designations for DBN1

  • developmentally-regulated brain protein
  • drebrin
  • drebrin E
  • drebrin E2
  • drebrin-1
  • drebrin A
  • developmentally regulated brain protein
  • drebrin 1
  • drebrin-like
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