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DARPP32 Products

(Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B))

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This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

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Featured DARPP32 Categories

DARPP32 Antibodies

High quality antibodies with extensive validation data.

DARPP32 ELISA Kits

Reliable ELISA kits for a wide range of species.

DARPP32 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DARPP32 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (5)
Cat. No. ABIN6255670
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (2)
  • (4)
Cat. No. ABIN1724929
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6255735
Quantity 100 μL
Datasheet Datasheet

Recommended DARPP32 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958944
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1571989
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380554
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended DARPP32 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315972
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406788
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2719226
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our DARPP32 products

Cunha, Matheus, Moretti, Sampaio, Poli, Santos, Colle, Cunha, Blum-Silva, Sandjo, Reginatto, Rodrigues, Farina, Prediger: "Agmatine attenuates reserpine-induced oral dyskinesia in mice: Role of oxidative stress, nitric oxide and glutamate NMDA receptors." in: Behavioural brain research, Vol. 312, pp. 64-76, (2016) (PubMed).

Bonito-Oliva, DuPont, Madjid, Ögren, Fisone: "Involvement of the Striatal Medium Spiny Neurons of the Direct Pathway in the Motor Stimulant Effects of Phencyclidine." in: The international journal of neuropsychopharmacology, (2016) (PubMed).

DelGuidice, Latapy, Rampino, Khlghatyan, Lemasson, Gelao, Quarto, Rizzo, Barbeau, Lamarre, Bertolino, Blasi, Beaulieu: "FXR1P is a GSK3β substrate regulating mood and emotion processing." in: Proceedings of the National Academy of Sciences of the United States of America, (2015) (PubMed).

Yabuki, Ohizumi, Yokosuka, Mimaki, Fukunaga: "Nobiletin treatment improves motor and cognitive deficits seen in MPTP-induced Parkinson model mice." in: Neuroscience, Vol. 259, pp. 126-41, (2014) (PubMed).

Gomez, Midde, Mactutus, Booze, Zhu: "Environmental enrichment alters nicotine-mediated locomotor sensitization and phosphorylation of DARPP-32 and CREB in rat prefrontal cortex." in: PLoS ONE, Vol. 7, Issue 8, pp. e44149, (2013) (PubMed).

Gulati, Cheung, Antrobus, Church, Harding, Tung, Rimmington, Ma, Ron, Lehner, Ashcroft, Cox, Coll, ORahilly, Yeo: "Role for the obesity-related FTO gene in the cellular sensing of amino acids." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 7, pp. 2557-62, (2013) (PubMed).

Cantrup, Sathanantham, Rushlow, Rajakumar: "Chronic hyperdopaminergic activity of schizophrenia is associated with increased ΔFosB levels and cdk-5 signaling in the nucleus accumbens." in: Neuroscience, Vol. 222, pp. 124-35, (2012) (PubMed).

Marazziti, Di Pietro, Mandillo, Golini, Matteoni, Tocchini-Valentini: "Absence of the GPR37/PAEL receptor impairs striatal Akt and ERK2 phosphorylation, DeltaFosB expression, and conditioned place preference to amphetamine and cocaine." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 6, pp. 2071-81, (2011) (PubMed).

Daigle, Wetsel, Caron: "Opposite function of dopamine D1 and N-methyl-D-aspartate receptors in striatal cannabinoid-mediated signaling." in: The European journal of neuroscience, Vol. 34, Issue 9, pp. 1378-89, (2011) (PubMed).

Kunii, Ikemoto, Wada, Yang, Kusakabe, Suzuki, Niwa: "Detailed DARPP-32 expression profiles in postmortem brains from patients with schizophrenia: an immunohistochemical study." in: Medical molecular morphology, Vol. 44, Issue 4, pp. 190-9, (2011) (PubMed).

Synonyms and alternative names related to DARPP32

protein phosphatase 1 regulatory inhibitor subunit 1B (ppp1r1b), protein phosphatase 1 regulatory inhibitor subunit 1B (PPP1R1B), protein phosphatase 1, regulatory (inhibitor) subunit 1B (Ppp1r1b), protein phosphatase 1 regulatory inhibitor subunit 1B S homeolog (ppp1r1b.S), AU040756, darpp-32, Darpp-32, DARPP-32, darpp32, Darpp32, DARPP32

Protein level used designations for DARPP32

  • protein phosphatase 1, regulatory (inhibitor) subunit 1B (dopamine and cAMP regulated phosphoprotein, DARPP-32)
  • neuronal phosphoprotein DARPP-32
  • protein phosphatase 1 regulatory subunit 1B
  • protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • dopamine- and cAMP-regulated neuronal phosphoprotein
  • dopamine- and cAMP-regulated phosphoprotein DARPP-32
  • dopamine and cAMP-regulated neuronal phosphoprotein 32
  • DARPP-32
  • dopamine and cAMP regulated
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