DARC Products
(Duffy Blood Group, Chemokine Receptor (DARC))
Categories
The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured DARC Categories
DARC Antibodies
High quality antibodies with extensive validation data.
DARC ELISA Kits
Reliable ELISA kits for a wide range of species.
DARC Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DARC Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (5)
Cat. No.
ABIN185480
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (4)
Cat. No.
ABIN515870
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7439006
Quantity
100 μL
Datasheet
Datasheet
Recommended DARC ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955472
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1569346
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5653752
Quantity
96 tests
Datasheet
Datasheet
Recommended DARC Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351113
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7394597
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7404320
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our DARC products
: "Prognostic significance of BIRC7/Livin, Bcl-2, p53, Annexin V, PD-L1, DARC, MSH2 and PMS2 in colorectal cancer treated with FOLFOX chemotherapy with or without aspirin." in: PLoS ONE, Vol. 16, Issue 1, pp. e0245581, (2021) (PubMed).: "Chemokine (C-C motif) ligand 2 and coronary artery disease: Tissue expression of functional and atypical receptors." in: Cytokine, Vol. 126, pp. 154923, (2020) (PubMed).
: "Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis." in: Nature immunology, Vol. 18, Issue 7, pp. 753-761, (2017) (PubMed).
: "Host genotype and tumor phenotype of chemokine decoy receptors integrally affect breast cancer relapse." in: Oncotarget, Vol. 6, Issue 28, pp. 26519-27, (2015) (PubMed).
: "Distinct Transcript Isoforms of the Atypical Chemokine Receptor 1 (ACKR1)/Duffy Antigen Receptor for Chemokines (DARC) Gene Are Expressed in Lymphoblasts and Altered Isoform Levels Are Associated ..." in: PLoS ONE, Vol. 10, Issue 10, pp. e0140098, (2015) (PubMed).
: "Absence of multiple atypical chemokine binders (ACBs) and the presence of VEGF and MMP-9 predict axillary lymph node metastasis in early breast carcinomas." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 9, pp. 145, (2014) (PubMed).
: "Extensive ex vivo expansion of functional human erythroid precursors established from umbilical cord blood cells by defined factors." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 22, Issue 2, pp. 451-463, (2014) (PubMed).
: "Coexpression of atypical chemokine binders (ACBs) in breast cancer predicts better outcomes." in: Breast cancer research and treatment, Vol. 125, Issue 3, pp. 715-27, (2011) (PubMed).
: "Dengue hemorrhagic fever is associated with polymorphisms in JAK1." in: European journal of human genetics : EJHG, Vol. 18, Issue 11, pp. 1221-7, (2010) (PubMed).
: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
Synonyms and alternative names related to DARC
Duffy blood group, chemokine receptor (DARC), atypical chemokine receptor 1 (Duffy blood group) (ACKR1), atypical chemokine receptor 1 (Ackr1), atypical chemokine receptor 1 (Duffy blood group) (Ackr1), AA162249, ACKR1, Ackr1, CCBP1, CD234, DARC, Dfy, ESTM35, FY, GPD, GpFy, WBCQ1Protein level used designations for DARC
- Duffy blood group, chemokine receptor
- duffy antigen/chemokine receptor
- Duffy antigen/chemokine receptor
- Duffy blood group antigen
- Fy glycoprotein
- atypical chemokine receptor 1
- glycoprotein D
- plasmodium vivax receptor
- Duffy antigen receptor for chemokines
- blood group antigen
- duffy antigen/receptor for chemokine glycoprotein
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