DAP3 Products
(Death-Associated Protein 3 (DAP3))
Categories
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Dec 2010].
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Featured DAP3 Categories
DAP3 Antibodies
High quality antibodies with extensive validation data.
DAP3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DAP3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (9)
Cat. No.
ABIN184743
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN948647
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7142266
Quantity
100 μL
Datasheet
Datasheet
Recommended DAP3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955294
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6215816
Quantity
96 tests
Datasheet
Datasheet
Recommended DAP3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351092
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351094
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7421338
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our DAP3 products
: "Substrate trapping proteomics reveals targets of the ?TrCP2/FBXW11 ubiquitin ligase." in: Molecular and cellular biology, Vol. 35, Issue 1, pp. 167-81, (2014) (PubMed).: "IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway." in: Oncogene, Vol. 21, Issue 15, pp. 2295-308, (2002) (PubMed).
: "The triterpenoid CDDO induces apoptosis in refractory CLL B cells." in: Blood, Vol. 100, Issue 8, pp. 2965-72, (2002) (PubMed).
: "An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis." in: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 22320-9, (2002) (PubMed).
: "Interaction of DAP3 and FADD only after cellular disruption." in: Nature immunology, Vol. 3, Issue 1, pp. 3-5, (2001) (PubMed).
: "Isolation of DAP3, a novel mediator of interferon-gamma-induced cell death." in: The Journal of biological chemistry, Vol. 270, Issue 46, pp. 27932-6, (1996) (PubMed).
Synonyms and alternative names related to DAP3
death associated protein 3 (DAP3), death associated protein 3 (Dap3), death associated protein 3 (dap3), 4921514D13Rik, bMRP-10, DAP-3, im:6905684, MRP-S29, MRPS29Protein level used designations for DAP3
- 28S ribosomal protein S29, mitochondrial
- S29mt
- death-associated protein 3
- ionizing radiation resistance conferring protein
- mitochondrial 28S ribosomal protein S29
- MRP-S29
- DAP-3
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