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DAP Kinase 1 Products

(Death-Associated Protein Kinase 1 (DAPK1))
Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. [provided by RefSeq, Jul 2008].

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Featured DAP Kinase 1 Categories

DAP Kinase 1 Antibodies

High quality antibodies with extensive validation data.

DAP Kinase 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

DAP Kinase 1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DAP Kinase 1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IF, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN391321
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
  • (1)
Cat. No. ABIN732983
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN6261221
Quantity 100 μL
Datasheet Datasheet

Recommended DAP Kinase 1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966274
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955295
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955296
Quantity 96 tests
Datasheet Datasheet

Recommended DAP Kinase 1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351098
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351096
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7317057
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our DAP Kinase 1 products

Bai, Zhang, Hu, Liu, Wang, Li, Lin, Zhang, Sun, Du, Song: "Silencing DNA methyltransferase 1 (DNMT1) inhibits proliferation, metastasis and invasion in ESCC by suppressing methylation of RASSF1A and DAPK." in: Oncotarget, Vol. 7, Issue 28, pp. 44129-44141, (2018) (PubMed).

Hearnden, Powers, Elmogassabi, Lowe, Murdoch: "Methyl-donor depletion of head and neck cancer cells in vitro establishes a less aggressive tumour cell phenotype." in: European journal of nutrition, (2017) (PubMed).

Liu, Ao, Zhou, Cui, Zhou, Yuan, Xiang, Cao, Liu: "CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine." in: Biochemical and biophysical research communications, Vol. 402, Issue 3, pp. 507-14, (2010) (PubMed).

Shohat, Spivak-Kroizman, Cohen, Bialik, Shani, Berrisi, Eisenstein, Kimchi: "The pro-apoptotic function of death-associated protein kinase is controlled by a unique inhibitory autophosphorylation-based mechanism." in: The Journal of biological chemistry, Vol. 276, Issue 50, pp. 47460-7, (2001) (PubMed).

Inbal, Shani, Cohen, Kissil, Kimchi: "Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis." in: Molecular and cellular biology, Vol. 20, Issue 3, pp. 1044-54, (2000) (PubMed).

Boesen-de Cock, Tepper, de Vries, van Blitterswijk, Borst: "Common regulation of apoptosis signaling induced by CD95 and the DNA-damaging stimuli etoposide and gamma-radiation downstream from caspase-8 activation." in: The Journal of biological chemistry, Vol. 274, Issue 20, pp. 14255-61, (1999) (PubMed).

Cock, Tepper, de Vries, van Blitterswijk, Borst: "CD95 (Fas/APO-1) induces ceramide formation and apoptosis in the absence of a functional acid sphingomyelinase." in: The Journal of biological chemistry, Vol. 273, Issue 13, pp. 7560-5, (1998) (PubMed).

Thome, Schneider, Hofmann, Fickenscher, Meinl, Neipel, Mattmann, Burns, Bodmer, Schröter, Scaffidi, Krammer, Peter, Tschopp: "Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors." in: Nature, Vol. 386, Issue 6624, pp. 517-21, (1997) (PubMed).

Cohen, Feinstein, Kimchi: "DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity." in: The EMBO journal, Vol. 16, Issue 5, pp. 998-1008, (1997) (PubMed).

Muzio, Chinnaiyan, Kischkel, ORourke, Shevchenko, Ni, Scaffidi, Bretz, Zhang, Gentz, Mann, Krammer, Peter, Dixit: "FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex." in: Cell, Vol. 85, Issue 6, pp. 817-27, (1996) (PubMed).

Synonyms and alternative names related to DAP Kinase 1

death-associated protein kinase 1 (LOC427465), death associated protein kinase 1 L homeolog (dapk1.L), death associated protein kinase 1 (DAPK1), death-associated protein kinase 1 (dapk1), death associated protein kinase 1 (dapk1), death associated protein kinase 1 S homeolog (dapk1.S), death-associated protein kinase 1 (DAPK1), death associated protein kinase 1 (Dapk1), 2310039H24Rik, 2810425C21Rik, AI642003, D13Ucla1, DAP-Kinase, dapk, DAPK, DAPK1, MGC81366, MGC83745, si:ch211-66i11.1, wu:fj09c03

Protein level used designations for DAP Kinase 1

  • death-associated protein kinase 1
  • death-associated protein kinase 1-like
  • DAP kinase 1
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