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CYR61 Proteins

(Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation. [provided by RefSeq, Sep 2011].
CYR61 Protein (AA 1-381) (GST tag) CYR61 Protein (AA 1-381) (GST tag) CYR61 Protein (AA 1-381) (GST tag) (ABIN1351026)

CYR61 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

CYR61 Protein (AA 25-381) (His tag) CYR61 Protein (AA 25-381) (His tag) CYR61 Protein (AA 25-381) (His tag) (ABIN7122563)

CYR61 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

CYR61 Protein (AA 293-381) (GST tag) CYR61 Protein (AA 293-381) (GST tag) CYR61 Protein (AA 293-381) (GST tag) (ABIN1351029)

CYR61 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

CYR61 Proteins by Origin

Find CYR61 Proteins for a variety of species such as anti-Human CYR61, anti-Mouse CYR61, anti-Chicken CYR61. The species listed below are among those available. Click on a link to go to the corresponding products.

CYR61 Proteins by Source

Here you will find CYR61 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CYR61 Proteins by Protein Type

Here you can find CYR61 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

CYR61 Proteins by Application

Find CYR61 Proteins validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

CYR61 Proteins by Biological Activity

Find CYR61 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular CYR61 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (16)
  • (1)
Cat. No. ABIN1351026
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122563
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351029
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351027
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN1880631
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN7318369
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN935294
Quantity 20 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7404950
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398866
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3009101
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Yeast
Validations
Cat. No. ABIN7478972
Quantity 100 μg
Datasheet Datasheet
Reactivity Chicken
Source Yeast
Validations
Cat. No. ABIN1458873
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1647221
Quantity 1 mg
Datasheet Datasheet
Reactivity Chimpanzee
Source Yeast
Validations
Cat. No. ABIN1654843
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CYR61 Proteins

Jeansonne, Pacifici, Lassak, Reiss, Russo, Zabaleta, Peruzzi: "Differential Effects of MicroRNAs on Glioblastoma Growth and Migration." in: Genes, Vol. 4, Issue 1, pp. 46-64, (2014) (PubMed).

Kok, Lin, Hou, Hong, Chang, Hsiao, Wang, Lai, Lin: "Simvastatin inhibits cysteine-rich protein 61 expression in rheumatoid arthritis synovial fibroblasts through the regulation of sirtuin-1/FoxO3a signaling." in: Arthritis and rheumatism, Vol. 65, Issue 3, pp. 639-49, (2013) (PubMed).

You, Yang, Yang, Chen: "Cyr61 induces the expression of monocyte chemoattractant protein-1 via the integrin ???3, FAK, PI3K/Akt, and NF-?B pathways in retinal vascular endothelial cells." in: Cellular signalling, Vol. 26, Issue 1, pp. 133-40, (2013) (PubMed).

Terada, Shiraishi, Zeng, Mooney, Yeater, Mangold, Partin, Kulkarni, Getzenberg: "Cyr61 is regulated by cAMP-dependent protein kinase with serum levels correlating with prostate cancer aggressiveness." in: The Prostate, Vol. 72, Issue 9, pp. 966-76, (2012) (PubMed).

Wu, Lin, Lee, Kok, Wang, Hou, Yang, Lai, Wang, Hong: "Epigallocatechin-3-gallate diminishes cytokine-stimulated Cyr61 expression in human osteoblastic cells: a therapeutic potential for arthritis." in: Rheumatology (Oxford, England), Vol. 51, Issue 11, pp. 1953-65, (2012) (PubMed).

Kok, Hou, Hong, Wang, Liang, Chang, Hsiao, Yang, Lai, Lin: "Simvastatin inhibits cytokine-stimulated Cyr61 expression in osteoblastic cells: a therapeutic benefit for arthritis." in: Arthritis and rheumatism, Vol. 63, Issue 4, pp. 1010-20, (2011) (PubMed).

Bär, Dorfman, Fischer, Hilfiker-Kleiner, Cebotari, Tudorache, Suprunov, Haverich, Hilfiker: "The pro-angiogenic factor CCN1 enhances the re-endothelialization of biological vascularized matrices in vitro." in: Cardiovascular research, Vol. 85, Issue 4, pp. 806-13, (2010) (PubMed).

Su, Chiou, Tang, Zhao, Tsai, Chen, Chang, Chien, Peng, Hsiao, Kuo, Yen: "CYR61 regulates BMP-2-dependent osteoblast differentiation through the {alpha}v{beta}3 integrin/integrin-linked kinase/ERK pathway." in: The Journal of biological chemistry, Vol. 285, Issue 41, pp. 31325-36, (2010) (PubMed).

You, Yang, Chen, Yang: "Regulation of Cyr61/CCN1 expression by hypoxia through cooperation of c-Jun/AP-1 and HIF-1? in retinal vascular endothelial cells." in: Experimental eye research, Vol. 91, Issue 6, pp. 825-36, (2010) (PubMed).

Chai, Norng, Modak, Reavis, Mouazzen, Pham: "CCN1 induces a reversible epithelial-mesenchymal transition in gastric epithelial cells." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 90, Issue 8, pp. 1140-51, (2010) (PubMed).

Aliases for CYR61 Proteins

cysteine rich angiogenic inducer 61 (CYR61) Proteins
cysteine-rich, angiogenic inducer, 61 (Cyr61) Proteins
cysteine rich angiogenic inducer 61 (cyr61) Proteins
cysteine-rich, angiogenic inducer, 61 like 2 (cyr61l2) Proteins
cysteine rich protein 61 (Cyr61) Proteins
cysteine rich angiogenic inducer 61 S homeolog (cyr61.S) Proteins
cysteine rich angiogenic inducer 61 (Cyr61) Proteins
AI325051 Proteins
CCN1 Proteins
ccn1 Proteins
CYR61 Proteins
cyr61-l2 Proteins
GIG1 Proteins
gig1 Proteins
IGFBP10 Proteins
igfbp10 Proteins
Igfbp10 Proteins
MGC69281 Proteins
MGC69539 Proteins
Xcyr61 Proteins
zgc:158158 Proteins
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