CYP3A7 Products
(Cytochrome P450, Family 3, Subfamily A, Polypeptide 7 (CYP3A7))
Categories
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced. This gene undergoes readthrough transcription with the downstream CYP3AP1 pseudogene, resulting in an isoform with a novel C-terminus, as represented in GeneID:100861540. [provided by RefSeq, Feb 2012].
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Featured CYP3A7 Categories
CYP3A7 Antibodies
High quality antibodies with extensive validation data.
CYP3A7 ELISA Kits
Reliable ELISA kits for a wide range of species.
CYP3A7 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CYP3A7 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7427744
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7149266
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN307113
Quantity
200 μg
Datasheet
Datasheet
Recommended CYP3A7 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955261
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648181
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5653517
Quantity
96 tests
Datasheet
Datasheet
Recommended CYP3A7 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350996
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350998
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7401020
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CYP3A7 products
: "Ontogeny of CYP3A and P-glycoprotein in the liver and the small intestine of the Göttingen minipig: an immunohistochemical evaluation." in: Basic & clinical pharmacology & toxicology, Vol. 114, Issue 5, pp. 387-94, (2014) (PubMed).: "Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 10, pp. 3758-65, (2005) (PubMed).
: "Variability of CYP3A7 expression in human fetal liver." in: The Journal of pharmacology and experimental therapeutics, Vol. 314, Issue 2, pp. 626-35, (2005) (PubMed).
: "Selective suppressions of human CYP3A forms, CYP3A5 and CYP3A7, by troglitazone in HepG2 cells." in: Drug metabolism and pharmacokinetics, Vol. 17, Issue 1, pp. 42-6, (2004) (PubMed).
Synonyms and alternative names related to CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7 (CYP3A7), cytochrome P450 family 3 subfamily A member 7 (CYP3A7), CP37, CYPIIIA7, P450-HFLAProtein level used designations for CYP3A7
- cytochrome P450 3A7
- aryl hydrocarbon hydroxylase
- cytochrome P450, subfamily IIIA, polypeptide 7
- cytochrome P450-HFLA
- flavoprotein-linked monooxygenase
- microsomal monooxygenase
- xenobiotic monooxygenase
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