CYP2E1 Products
(Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
Categories
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. [provided by RefSeq, Jul 2008].
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Featured CYP2E1 Categories
CYP2E1 Antibodies
High quality antibodies with extensive validation data.
CYP2E1 ELISA Kits
Reliable ELISA kits for a wide range of species.
CYP2E1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CYP2E1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7438247
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (1)
- (4)
Cat. No.
ABIN3023079
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (3)
- (5)
Cat. No.
ABIN3043821
Quantity
100 μg
Datasheet
Datasheet
Recommended CYP2E1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
Cat. No.
ABIN6720507
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (7)
- (1)
Cat. No.
ABIN6955251
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6975637
Quantity
96 tests
Datasheet
Datasheet
Recommended CYP2E1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122582
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350977
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350976
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our CYP2E1 products
: "Oxidative Stress Parameters in the Liver of Growing Male Rats Receiving Various Alcoholic Beverages." in: Nutrients, Vol. 12, Issue 1, (2020) (PubMed).: "Alcohol-induced autophagy via upregulation of PIASy promotes HCV replication in human hepatoma cells." in: Cell death & disease, Vol. 9, Issue 9, pp. 898, (2018) (PubMed).
: "Liver atrophy after percutaneous transhepatic portal embolization occurs in two histological phases: Hepatocellular atrophy followed by apoptosis." in: World journal of hepatology, Vol. 9, Issue 32, pp. 1227-1238, (2017) (PubMed).
: "Gpr110 deficiency decelerates carcinogen-induced hepatocarcinogenesis via activation of the IL-6/STAT3 pathway." in: American journal of cancer research, Vol. 7, Issue 3, pp. 433-447, (2017) (PubMed).
: "WNT5A Inhibits Hepatocyte Proliferation and Concludes ?-Catenin Signaling in Liver Regeneration." in: The American journal of pathology, Vol. 185, Issue 8, pp. 2194-205, (2015) (PubMed).
: "The role of intestinal microbiota in murine models of acetaminophen-induced hepatotoxicity." in: Liver international : official journal of the International Association for the Study of the Liver, (2014) (PubMed).
: "PASS-predicted hepatoprotective activity of Caesalpinia sappan in thioacetamide-induced liver fibrosis in rats." in: TheScientificWorldJournal, Vol. 2014, pp. 301879, (2014) (PubMed).
: "Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 143, Issue 1, pp. 107-15, (2014) (PubMed).
: "Wuzhi tablet (Schisandra Sphenanthera extract) protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of NRF2-ARE and p53/p21 pathways." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 42, Issue 12, pp. 1982-90, (2014) (PubMed).
: "Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. ..." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 2, pp. 397-406, (2014) (PubMed).
Synonyms and alternative names related to CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1 (CYP2E1), cytochrome P450 2E1 (CYP2E1), cytochrome P450 2E1 (PTRG_07411), cytochrome P450 2E1 (LOC100342572), cytochrome P450 2E1 (LOC100727914), cytochrome P450 2E1-like (LOC101843716), cytochrome P450 family 2 subfamily E member 1 (CYP2E1), cytochrome P450, family 2, subfamily e, polypeptide 1 (Cyp2e1), CPE1, CYP2E, Cyp2e, CYP2E1, CYPIIE1, P450-J, P450C2EProtein level used designations for CYP2E1
- cytochrome P450 2E1
- 4-nitrophenol 2-hydroxylase
- Cytochrome P450 2E1
- Cytochrome P450 LM3A
- Cytochrome P450 isozyme 3A
- Cytochrome P450-ALC
- Cytochrome P450-J
- cytochrome P-450j
- CYPIIE1
- cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1
- cytochrome P450-J
- flavoprotein-linked monooxygenase
- microsomal monooxygenase
- xenobiotic monooxygenase
- cytochrome P450, 2e1, ethanol inducible
- cytochrome P450-ALC
- P450-J
- P450RLM6
- cytochrome P450 subfamily 2e1 (ethanol-inducible)
- cytochrome P450, subfamily 2E, polypeptide 1
- cytochrome P450RLM6
- cytochrome P-450-J
- cytochrome P450 CYP2E1
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