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CYP2C9 Products

(Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9))
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008].

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Featured CYP2C9 Categories

CYP2C9 Antibodies

High quality antibodies with extensive validation data.

CYP2C9 ELISA Kits

Reliable ELISA kits for a wide range of species.

CYP2C9 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CYP2C9 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN681208
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN1882233
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN392355
Quantity 400 μL
Datasheet Datasheet

Recommended CYP2C9 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966238
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955246
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955247
Quantity 96 tests
Datasheet Datasheet

Recommended CYP2C9 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350972
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409971
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3078089
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CYP2C9 products

Zhang, Lou, Zhang, Zhang, Wang, Xu, Niu, Wang, Wu, Cui: "Hyperhomocysteinemia results from and promotes hepatocellular carcinoma via CYP450 metabolism by CYP2J2 DNA methylation." in: Oncotarget, Vol. 8, Issue 9, pp. 15377-15392, (2017) (PubMed).

Strick-Marchand, Dusséaux, Darche, Huntington, Legrand, Masse-Ranson, Corcuff, Ahodantin, Weijer, Spits, Kremsdorf, Di Santo: "A novel mouse model for stable engraftment of a human immune system and human hepatocytes." in: PLoS ONE, Vol. 10, Issue 3, pp. e0119820, (2015) (PubMed).

Yang, Cui, Hasi, Jia, Gong, Su: "Genetic polymorphisms of cytochrome P450 enzymes 2C9 and 2C19 in a healthy Mongolian population in China." in: Genetics and molecular research : GMR, Vol. 9, Issue 3, pp. 1844-51, (2010) (PubMed).

Ikejiri, Wada, Sakamoto, Ito, Nishioka, Nakatani, Tsuji, Yamada, Nakamura, Ito, Nobori: "The association of protein S Tokushima-K196E with a risk of deep vein thrombosis." in: International journal of hematology, Vol. 92, Issue 2, pp. 302-5, (2010) (PubMed).

Schelleman, Brensinger, Chen, Finkelman, Rieder, Kimmel: "New genetic variant that might improve warfarin dose prediction in African Americans." in: British journal of clinical pharmacology, Vol. 70, Issue 3, pp. 393-9, (2010) (PubMed).

Ng, Imaoka, Hiroi, Osada, Niwa, Kamataki, Funae: "Production of inhibitory polyclonal antibodies against cytochrome P450s." in: Drug metabolism and pharmacokinetics, Vol. 18, Issue 3, pp. 163-72, (2004) (PubMed).

Werck-Reichhart, Feyereisen: "Cytochromes P450: a success story." in: Genome biology, Vol. 1, Issue 6, pp. REVIEWS3003, (2001) (PubMed).

Synonyms and alternative names related to CYP2C9

cytochrome P450 family 2 subfamily C member 9 (CYP2C9), CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9

Protein level used designations for CYP2C9

  • cytochrome P-450 S-mephenytoin 4-hydroxylase
  • cytochrome P-450MP
  • cytochrome P450 2C9
  • cytochrome P450 PB-1
  • flavoprotein-linked monooxygenase
  • microsomal monooxygenase
  • xenobiotic monooxygenase
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