CYP2C9 Products
(Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9))
Categories
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008].
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Featured CYP2C9 Categories
CYP2C9 Antibodies
High quality antibodies with extensive validation data.
CYP2C9 ELISA Kits
Reliable ELISA kits for a wide range of species.
CYP2C9 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CYP2C9 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN681208
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
- (1)
Cat. No.
ABIN1882233
Quantity
0.1 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN392355
Quantity
400 μL
Datasheet
Datasheet
Recommended CYP2C9 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966238
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955246
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955247
Quantity
96 tests
Datasheet
Datasheet
Recommended CYP2C9 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350972
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7409971
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3078089
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CYP2C9 products
: "Hyperhomocysteinemia results from and promotes hepatocellular carcinoma via CYP450 metabolism by CYP2J2 DNA methylation." in: Oncotarget, Vol. 8, Issue 9, pp. 15377-15392, (2017) (PubMed).: "A novel mouse model for stable engraftment of a human immune system and human hepatocytes." in: PLoS ONE, Vol. 10, Issue 3, pp. e0119820, (2015) (PubMed).
: "Genetic polymorphisms of cytochrome P450 enzymes 2C9 and 2C19 in a healthy Mongolian population in China." in: Genetics and molecular research : GMR, Vol. 9, Issue 3, pp. 1844-51, (2010) (PubMed).
: "The association of protein S Tokushima-K196E with a risk of deep vein thrombosis." in: International journal of hematology, Vol. 92, Issue 2, pp. 302-5, (2010) (PubMed).
: "New genetic variant that might improve warfarin dose prediction in African Americans." in: British journal of clinical pharmacology, Vol. 70, Issue 3, pp. 393-9, (2010) (PubMed).
: "Production of inhibitory polyclonal antibodies against cytochrome P450s." in: Drug metabolism and pharmacokinetics, Vol. 18, Issue 3, pp. 163-72, (2004) (PubMed).
: "Cytochromes P450: a success story." in: Genome biology, Vol. 1, Issue 6, pp. REVIEWS3003, (2001) (PubMed).
Synonyms and alternative names related to CYP2C9
cytochrome P450 family 2 subfamily C member 9 (CYP2C9), CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9Protein level used designations for CYP2C9
- cytochrome P-450 S-mephenytoin 4-hydroxylase
- cytochrome P-450MP
- cytochrome P450 2C9
- cytochrome P450 PB-1
- flavoprotein-linked monooxygenase
- microsomal monooxygenase
- xenobiotic monooxygenase
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