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CYP27A1 Products

(Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1))

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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. [provided by RefSeq, Jul 2008].

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Featured CYP27A1 Categories

CYP27A1 Antibodies

High quality antibodies with extensive validation data.

CYP27A1 ELISA Kits

Reliable ELISA kits for a wide range of species.

CYP27A1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CYP27A1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (5)
Cat. No. ABIN2855688
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7170770
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6258060
Quantity 100 μL
Datasheet Datasheet

Recommended CYP27A1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6955255
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648175
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1159817
Quantity 96 tests
Datasheet Datasheet

Recommended CYP27A1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350952
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7407904
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2712758
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our CYP27A1 products

Zhao, Li, Wang, Habib, Wei, Sun, Strobel, Jia: "Vitamin D serum level is associated with Child-Pugh score and metabolic enzyme imbalances, but not viral load in chronic hepatitis B patients." in: Medicine, Vol. 95, Issue 27, pp. e3926, (2016) (PubMed).

Duan, Fu, Wang, Ni, Zhao: "Cholesterol deregulation induced by chronic corticosterone (CORT) stress in pectoralis major of broiler chickens." in: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, Vol. 176, pp. 59-64, (2014) (PubMed).

Haag, Stadel, Zhou, Bachem, Möller, Debatin, Fulda: "Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells." in: Gut, Vol. 60, Issue 2, pp. 225-37, (2011) (PubMed).

Korzekwa, Bah, Kurzynowski, Lukasik, Groblewska, Skarzynski: "Leukotrienes modulate secretion of progesterone and prostaglandins during the estrous cycle and early pregnancy in cattle: an in vivo study." in: Reproduction (Cambridge, England), Vol. 140, Issue 5, pp. 767-76, (2011) (PubMed).

Szlago, Gallus, Schenone, Patiño, Sfaelo, Rufa, Da Pozzo, Cardaioli, Dotti, Federico: "The first cerebrotendinous xanthomatosis family from Argentina: a new mutation in CYP27A1 gene." in: Neurology, Vol. 70, Issue 5, pp. 402-4, (2008) (PubMed).

Synonyms and alternative names related to CYP27A1

cytochrome P450 family 27 subfamily A member 1 (CYP27A1), cytochrome P450, family 27, subfamily a, polypeptide 1 (Cyp27a1), cytochrome P450, family 27, subfamily A, polypeptide 1 (CYP27A1), sterol 26-hydroxylase, mitochondrial (CYP27A1), cytochrome P450, family 27, subfamily A, polypeptide 1 (cyp27a1), 1300013A03Rik, CP27, CTX, CYP27, Cyp27, P450C27

Protein level used designations for CYP27A1

  • 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 26-hydroxylase
  • 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 27-hydroxylase
  • 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase
  • cholestanetriol 26-monooxygenase
  • cytochrome P-450C27/25
  • cytochrome P450 27
  • cytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1
  • sterol 26-hydroxylase, mitochondrial
  • sterol 27-hydroxylase
  • vitamin D(3) 25-hydroxylase
  • cytochrome P-450c27/25
  • cholesterol 27 hydroxylase
  • cytochrome P450, 27
  • cytochrome P450, 27a1
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