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CYP26B1 Products

(Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1))

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This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013].

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Featured CYP26B1 Categories

CYP26B1 Antibodies

High quality antibodies with extensive validation data.

CYP26B1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CYP26B1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, FACS
Validations
  • (5)
Cat. No. ABIN185731
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN527926
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6261169
Quantity 100 μL
Datasheet Datasheet

Recommended CYP26B1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6214669
Quantity 96 tests
Datasheet Datasheet

Recommended CYP26B1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350948
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350946
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415386
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CYP26B1 products

Foti, Isoherranen, Zelter, Dickmann, Buttrick, Diaz, Douguet: "Identification of Tazarotenic Acid as the First Xenobiotic Substrate of Human Retinoic Acid Hydroxylase CYP26A1 and CYP26B1." in: The Journal of pharmacology and experimental therapeutics, Vol. 357, Issue 2, pp. 281-92, (2016) (PubMed).

Chen, Lee, Hsu, Chen, Wang, Chen, Wang, Huang, Huang: "Expression of a splice variant of CYP26B1 in betel quid-related oral cancer." in: TheScientificWorldJournal, Vol. 2014, pp. 810561, (2014) (PubMed).

Elmabsout, Kumawat, Saenz-Méndez, Krivospitskaya, Sävenstrand, Olofsson, Eriksson, Strid, Valen, Törmä, Sirsjö: "Cloning and functional studies of a splice variant of CYP26B1 expressed in vascular cells." in: PLoS ONE, Vol. 7, Issue 5, pp. e36839, (2012) (PubMed).

Topletz, Thatcher, Zelter, Lutz, Tay, Nelson, Isoherranen: "Comparison of the function and expression of CYP26A1 and CYP26B1, the two retinoic acid hydroxylases." in: Biochemical pharmacology, Vol. 83, Issue 1, pp. 149-63, (2011) (PubMed).

Chen, Lee, Chen, Shieh, Ho, Wang, Lee, Yang, Chen, Chiang, Ko: "CYP26B1 is a novel candidate gene for betel quid-related oral squamous cell carcinoma." in: Oral oncology, Vol. 47, Issue 7, pp. 594-600, (2011) (PubMed).

Tay, Dickmann, Dixit, Isoherranen: "A comparison of the roles of peroxisome proliferator-activated receptor and retinoic acid receptor on CYP26 regulation." in: Molecular pharmacology, Vol. 77, Issue 2, pp. 218-27, (2010) (PubMed).

Pavez Loriè, Li, Vahlquist, Törmä: "The involvement of cytochrome p450 (CYP) 26 in the retinoic acid metabolism of human epidermal keratinocytes." in: Biochimica et biophysica acta, Vol. 1791, Issue 3, pp. 220-8, (2009) (PubMed).

Bowles, Knight, Smith, Wilhelm, Richman, Mamiya, Yashiro, Chawengsaksophak, Wilson, Rossant, Hamada, Koopman: "Retinoid signaling determines germ cell fate in mice." in: Science (New York, N.Y.), Vol. 312, Issue 5773, pp. 596-600, (2006) (PubMed).

Synonyms and alternative names related to CYP26B1

cytochrome P450 26B1 (CpipJ_CPIJ002537), cytochrome P450 family 26 subfamily B member 1 L homeolog (cyp26b1.L), cytochrome P450 family 26 subfamily B member 1 (CYP26B1), cytochrome P450 family 26 subfamily B member 1 (cyp26b1), cytochrome P450, family 26, subfamily B, polypeptide 1 (CYP26B1), cytochrome P450, family 26, subfamily b, polypeptide 1 (Cyp26b1), cytochrome P450, family 26, subfamily b, polypeptide 1 (cyp26b1), CP26, cyp26a2, CYP26A2, cyp26b1, fc21d03, p450rai-2, P450RAI-2, P450RAI2, RHFCA, wu:fc21d03, wu:fc26h10, zgc:76999

Protein level used designations for CYP26B1

  • cytochrome P450 26B1
  • cytochrome P450, family 26, subfamily B, polypeptide 1
  • cytochrome P450 retinoic acid-inactivating 2
  • cytochrome P450 retinoid metabolizing protein
  • cytochrome P450, subfamily XXVIB, polypeptide 1
  • retinoic acid-metabolizing cytochrome
  • cytochrome P450, 26, retinoic acid B1
  • cytochrome P450RAI-2
  • retinoic acid B1
  • retinoic acid hydroxylase
  • dol
  • stocksteif
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