CYP26A1 Products
(Cytochrome P450, Family 26, Subfamily A, Polypeptide 1 (CYP26A1))
Categories
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq, Jul 2008].
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Featured CYP26A1 Categories
CYP26A1 Antibodies
High quality antibodies with extensive validation data.
CYP26A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
CYP26A1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CYP26A1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN7266654
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, FACS
Validations
- (5)
Cat. No.
ABIN3030691
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), FACS
Validations
- (3)
Cat. No.
ABIN650717
Quantity
400 μL
Datasheet
Datasheet
Recommended CYP26A1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966246
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955254
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648174
Quantity
96 tests
Datasheet
Datasheet
Recommended CYP26A1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397558
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7406557
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3078000
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CYP26A1 products
: "The expression and prognostic significance of retinoic acid metabolising enzymes in colorectal cancer." in: PLoS ONE, Vol. 9, Issue 3, pp. e90776, (2014) (PubMed).: "Conserved sex-specific timing of meiotic initiation during sex differentiation in the protandrous black porgy Acanthopagrus schlegelii." in: Biology of reproduction, Vol. 88, Issue 6, pp. 150, (2013) (PubMed).
: "Pharmacogenomic analysis of acute promyelocytic leukemia cells highlights CYP26 cytochrome metabolism in differential all-trans retinoic acid sensitivity." in: Blood, Vol. 109, Issue 10, pp. 4450-60, (2007) (PubMed).
: "The discovery of new coding alleles of human CYP26A1 that are potentially defective in the metabolism of all-trans retinoic acid and their assessment in a recombinant cDNA expression system." in: Pharmacogenetics and genomics, Vol. 17, Issue 3, pp. 169-80, (2007) (PubMed).
: "Skin retinoid concentrations are modulated by CYP26AI expression restricted to basal keratinocytes in normal human skin and differentiated 3D skin models." in: The Journal of investigative dermatology, Vol. 126, Issue 11, pp. 2473-80, (2006) (PubMed).
: "Expression of the retinoic acid-metabolizing enzyme CYP26A1 limits programmed cell death." in: Molecular pharmacology, Vol. 67, Issue 5, pp. 1808-17, (2005) (PubMed).
: "Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 10, pp. 3758-65, (2005) (PubMed).
: "CYP26A1 and CYP26C1 cooperate in degrading retinoic acid within the equatorial retina during later eye development." in: Developmental biology, Vol. 276, Issue 1, pp. 143-57, (2004) (PubMed).
Synonyms and alternative names related to CYP26A1
cytochrome P450 family 26 subfamily A member 1 (CYP26A1), cytochrome P450, family 26, subfamily a, polypeptide 1 (Cyp26a1), cytochrome P450 family 26 subfamily A member 1 S homeolog (cyp26a1.S), cytochrome P450 family 26 subfamily A member 1 L homeolog (cyp26a1.L), cytochrome P450, family 26, subfamily A, polypeptide 1 (CYP26A1), cytochrome P450 family 26 subfamily A member 1 (cyp26a1), cytochrome P450, family 26, subfamily A, polypeptide 1 (cyp26a1), cb24, CP26, cp26, CYP26, Cyp26, cyp26, CYP26A, id:ibd5061, P450RA, P450RAI, p450rai, P450RAI1, p450rai1, RACE, RAH, wu:fb81e05, xCYP26, XCYP26A1Protein level used designations for CYP26A1
- P450, retinoic acid-inactivating, 1
- cytochrome P450 26A1
- cytochrome P450 retinoic acid-inactivating 1
- cytochrome P450, subfamily XXVIA, polypeptide 1
- cytochrome P450RAI
- hP450RAI
- retinoic acid 4-hydroxylase
- retinoic acid-metabolizing cytochrome
- cytochrome P450, 26, retinoic acid A1
- retinoic acid hydrolase
- RACE
- retinoic acid-converting enzyme
- retinoic acid-degrading enzyme CYP26
- xCYP26
- cytochrome P450, 26, retinoic acid
- retinoic acid hydroxylase
- retinoic acid converting enzyme
- cytochrome P450 retinoic acid hydroxylase
- cytochrome P450 26
- etID42255.12
- gir
- giraffe
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