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CYP24A1 Products

(Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured CYP24A1 Categories

CYP24A1 Antibodies

High quality antibodies with extensive validation data.

CYP24A1 ELISA Kits

Reliable ELISA kits for a wide range of species.

CYP24A1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CYP24A1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (4)
Cat. No. ABIN750838
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (3)
Cat. No. ABIN514852
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN1679472
Quantity 100 μg
Datasheet Datasheet

Recommended CYP24A1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966244
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966245
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955253
Quantity 96 tests
Datasheet Datasheet

Recommended CYP24A1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350944
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7397561
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406554
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CYP24A1 products

Smolders, Schuurman, van Strien, Melief, Hendrickx, Hol, van Eden, Luchetti, Huitinga: "Expression of vitamin D receptor and metabolizing enzymes in multiple sclerosis-affected brain tissue." in: Journal of neuropathology and experimental neurology, Vol. 72, Issue 2, pp. 91-105, (2013) (PubMed).

Kotani, Tanabe, Mizukami, Amagaya, Inoue: "A naturally occurring rexinoid, honokiol, can serve as a regulator of various retinoid x receptor heterodimers." in: Biological & pharmaceutical bulletin, Vol. 35, Issue 1, pp. 1-9, (2012) (PubMed).

Helvig, Cuerrier, Hosfield, Ireland, Kharebov, Kim, Ramjit, Ryder, Tabash, Herzenberg, Epps, Petkovich: "Dysregulation of renal vitamin D metabolism in the uremic rat." in: Kidney international, Vol. 78, Issue 5, pp. 463-72, (2010) (PubMed).

Shen, Bielak, Ferguson, Streeten, Yerges-Armstrong, Liu, Post, OConnell, Hixson, Kardia, Sun, Jhun, Wang, Mehta, Li, Koller, Hakonarson, Keating, Rader, Shuldiner, Peyser, Reilly, Mitchell: "Association of the vitamin D metabolism gene CYP24A1 with coronary artery calcification." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 30, Issue 12, pp. 2648-54, (2010) (PubMed).

Peng, Jhaveri, Hussain-Hakimjee, Mehta: "Overexpression of ER and VDR is not sufficient to make ER-negative MDA-MB231 breast cancer cells responsive to 1alpha-hydroxyvitamin D5." in: Carcinogenesis, Vol. 28, Issue 5, pp. 1000-7, (2007) (PubMed).

Synonyms and alternative names related to CYP24A1

cytochrome P450 family 24 subfamily A member 1 (CYP24A1), cytochrome P450, family 24, subfamily a, polypeptide 1 (Cyp24a1), cytochrome P450, family 24, subfamily A, polypeptide 1 (CYP24A1), 24-OHase, 25-hydroxyvitaminD324-hydroxylase, CP24, CP450CC24, CYP24, Cyp24, HCAI, P450-CC24, VITD12

Protein level used designations for CYP24A1

  • 1,25-@dihydroxyvitamin D3 24-hydroxylase
  • 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
  • 24-OHase
  • cytochrome P450 24A1
  • cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase)
  • cytochrome P450-CC24
  • exo-mitochondrial protein
  • vitamin D 24-hydroxylase
  • vitamin D(3) 24-hydroxylase
  • 25-hydroxyvitamin D-24-hydroxylase
  • cytochrome P450, 24
  • cytochrome P450, 24a1
  • 24R-Ohase
  • 25-hydroxyvitamin D3 24-hydroxylase
  • Cytochrom P450 (25-hydroxyvitamin D24-hydroxylase)
  • P450-CC24
  • cytochrome P450, subfamily 24
  • 25-hydroxyvitamin D3-24-hydroxylase
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