CYP24A1 Products
(Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
Categories
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured CYP24A1 Categories
CYP24A1 Antibodies
High quality antibodies with extensive validation data.
CYP24A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
CYP24A1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CYP24A1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN750838
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (3)
Cat. No.
ABIN514852
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN1679472
Quantity
100 μg
Datasheet
Datasheet
Recommended CYP24A1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966244
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966245
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955253
Quantity
96 tests
Datasheet
Datasheet
Recommended CYP24A1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350944
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397561
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7406554
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CYP24A1 products
: "Expression of vitamin D receptor and metabolizing enzymes in multiple sclerosis-affected brain tissue." in: Journal of neuropathology and experimental neurology, Vol. 72, Issue 2, pp. 91-105, (2013) (PubMed).: "A naturally occurring rexinoid, honokiol, can serve as a regulator of various retinoid x receptor heterodimers." in: Biological & pharmaceutical bulletin, Vol. 35, Issue 1, pp. 1-9, (2012) (PubMed).
: "Dysregulation of renal vitamin D metabolism in the uremic rat." in: Kidney international, Vol. 78, Issue 5, pp. 463-72, (2010) (PubMed).
: "Association of the vitamin D metabolism gene CYP24A1 with coronary artery calcification." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 30, Issue 12, pp. 2648-54, (2010) (PubMed).
: "Overexpression of ER and VDR is not sufficient to make ER-negative MDA-MB231 breast cancer cells responsive to 1alpha-hydroxyvitamin D5." in: Carcinogenesis, Vol. 28, Issue 5, pp. 1000-7, (2007) (PubMed).
Synonyms and alternative names related to CYP24A1
cytochrome P450 family 24 subfamily A member 1 (CYP24A1), cytochrome P450, family 24, subfamily a, polypeptide 1 (Cyp24a1), cytochrome P450, family 24, subfamily A, polypeptide 1 (CYP24A1), 24-OHase, 25-hydroxyvitaminD324-hydroxylase, CP24, CP450CC24, CYP24, Cyp24, HCAI, P450-CC24, VITD12Protein level used designations for CYP24A1
- 1,25-@dihydroxyvitamin D3 24-hydroxylase
- 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
- 24-OHase
- cytochrome P450 24A1
- cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase)
- cytochrome P450-CC24
- exo-mitochondrial protein
- vitamin D 24-hydroxylase
- vitamin D(3) 24-hydroxylase
- 25-hydroxyvitamin D-24-hydroxylase
- cytochrome P450, 24
- cytochrome P450, 24a1
- 24R-Ohase
- 25-hydroxyvitamin D3 24-hydroxylase
- Cytochrom P450 (25-hydroxyvitamin D24-hydroxylase)
- P450-CC24
- cytochrome P450, subfamily 24
- 25-hydroxyvitamin D3-24-hydroxylase
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