CYP1B1 Products
(Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))
Categories
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma\; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq, Jul 2008].
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Featured CYP1B1 Categories
CYP1B1 Antibodies
High quality antibodies with extensive validation data.
CYP1B1 ELISA Kits
Reliable ELISA kits for a wide range of species.
CYP1B1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CYP1B1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN3021931
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN7257375
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6261168
Quantity
100 μL
Datasheet
Datasheet
Recommended CYP1B1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966227
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966226
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955232
Quantity
96 tests
Datasheet
Datasheet
Recommended CYP1B1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350941
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397372
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3091856
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CYP1B1 products
: "Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[a]Pyrene Metabolite Profile and Its Distribution in 3D Skin." in: mBio, Vol. 12, Issue 5, pp. e0122321, (2022) (PubMed).: "Seasonal Variation in the Biological Effects of PM2.5 from Greater Cairo." in: International journal of molecular sciences, Vol. 20, Issue 20, (2019) (PubMed).
: "In vitro lung toxicity of indoor PM10 from a stove fueled with different biomasses." in: The Science of the total environment, Vol. 649, pp. 1422-1433, (2018) (PubMed).
: "LRH-1 mediates anti-inflammatory and antifungal phenotype of IL-13-activated macrophages through the PPARγ ligand synthesis." in: Nature communications, Vol. 6, pp. 6801, (2015) (PubMed).
: "Human skin-derived stem cells as a novel cell source for in vitro hepatotoxicity screening of pharmaceuticals." in: Stem cells and development, Vol. 23, Issue 1, pp. 44-55, (2013) (PubMed).
: "TGF-?1 signaling plays a dominant role in the crosstalk between TGF-?1 and the aryl hydrocarbon receptor ligand in prostate epithelial cells." in: Cellular signalling, Vol. 24, Issue 8, pp. 1665-76, (2012) (PubMed).
: "Aryl hydrocarbon receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 2, pp. 644-52, (2011) (PubMed).
: "Estrogen and cytochrome P450 1B1 contribute to both early- and late-stage head and neck carcinogenesis." in: Cancer prevention research (Philadelphia, Pa.), Vol. 4, Issue 1, pp. 107-15, (2011) (PubMed).
: "Early changes in gene expression induced by tobacco smoke: Evidence for the importance of estrogen within lung tissue." in: Cancer prevention research (Philadelphia, Pa.), Vol. 3, Issue 6, pp. 707-17, (2010) (PubMed).
: "HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling." in: The Journal of biological chemistry, Vol. 284, Issue 12, pp. 7436-45, (2009) (PubMed).
Synonyms and alternative names related to CYP1B1
cytochrome P450 family 1 subfamily B member 1 (CYP1B1), cytochrome P450, family 1, subfamily b, polypeptide 1 (Cyp1b1), cytochrome P450, family 1, subfamily B, polypeptide 1 (CYP1B1), cytochrome P450 1B1 (CYP1B1), cytochrome P450, family 1, subfamily B, polypeptide 1 (cyp1b1), cytochrome P450 1B1 (LOC100719054), CP1B, CYP1B, CYP1B1, CYPIB1, GLC3A, P4501B1, P4501b1, zgc:136223Protein level used designations for CYP1B1
- aryl hydrocarbon hydroxylase
- cytochrome P450 1B1
- cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile)
- flavoprotein-linked monooxygenase
- microsomal monooxygenase
- xenobiotic monooxygenase
- CYPIB1
- benz[a]anthracene inducible
- cytochrome P450, 1b1, benz[a]anthracene inducible
- cytochrome P450CMEF
- cytochrome P450EF
- P450RAP
- cytochrome P450, subfamily 1B, polypeptide 1
- cytochrome P450RAP
- cytochrome P4501B
- cytochrome P450, family 1, subfamily B, polypeptide 1
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