CYP17A1 Products
(Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))
Categories
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008].
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Featured CYP17A1 Categories
CYP17A1 Antibodies
High quality antibodies with extensive validation data.
CYP17A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
CYP17A1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CYP17A1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (3)
- (5)
Cat. No.
ABIN720071
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7170749
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
Cat. No.
ABIN6258050
Quantity
100 μL
Datasheet
Datasheet
Recommended CYP17A1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966231
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955239
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648173
Quantity
96 tests
Datasheet
Datasheet
Recommended CYP17A1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350928
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419073
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7418737
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CYP17A1 products
: "Seasonal expression of P450c17 and 5α-reductase-2 in the scented gland of male muskrats (Ondatra zibethicus)." in: General and comparative endocrinology, Vol. 254, pp. 60-67, (2018) (PubMed).: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).
: "Effect of Different Doses of Oral Cholecalciferol on Serum 1,25(OH)2D in Vitamin D Deficient Schoolchildren." in: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme, Vol. 48, Issue 6, pp. 394-8, (2017) (PubMed).
: "Estrogen Suppresses Interaction of Melanocortin 2 Receptor and Its Accessory Protein in the Primate Fetal Adrenal Cortex." in: Endocrinology, Vol. 157, Issue 12, pp. 4588-4601, (2017) (PubMed).
: "Differential response to abiraterone acetate and di-n-butyl phthalate in an androgen-sensitive human fetal testis xenograft bioassay." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 138, Issue 1, pp. 148-60, (2014) (PubMed).
: "Molecular characterization of enzalutamide-treated bone metastatic castration-resistant prostate cancer." in: European urology, Vol. 67, Issue 1, pp. 53-60, (2014) (PubMed).
: "Ovarian and placental morphology and endocrine functions in the pregnant giraffe (Giraffa camelopardalis)." in: Reproduction (Cambridge, England), Vol. 145, Issue 6, pp. 541-54, (2013) (PubMed).
: "Effects of abiraterone acetate on androgen signaling in castrate-resistant prostate cancer in bone." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 30, Issue 6, pp. 637-43, (2012) (PubMed).
: "CYP17 polymorphism as a risk factor of tamoxifen-induced hepatic steatosis in breast cancer patients." in: Oncology reports, Vol. 13, Issue 3, pp. 485-9, (2005) (PubMed).
Synonyms and alternative names related to CYP17A1
cytochrome P450 17A1 (CpipJ_CPIJ010537), cytochrome P450 17A1 (CpipJ_CPIJ010543), cytochrome P450 17A1 (PTRG_02047), cytochrome P450, family 17, subfamily A, polypeptide 1 (cyp17a1), steroidogenic cytochrome P450 17-hydroxylase/lyase (cyp17), cytochrome P450 family 17 subfamily A member 1 L homeolog (cyp17a1.L), cytochrome P450 family 17 subfamily A member 1 (cyp17a1), cytochrome P-450 17 alpha-hydroxylase/C17,20-lyase (CYP17A1), cytochrome P450 17A1 (CYP17A1), cytochrome P450 family 17 subfamily A member 1 (CYP17A1), cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), cytochrome P450, family 17, subfamily a, polypeptide 1 (Cyp17a1), cytochrome P450c17 (CYP17A1), CPT7, cyp17, CYP17, Cyp17, cyp17a1, CYPXVII, P450-C17, P450c17, P450C17, p450c17, P45017A1, S17AH, wu:fi13g04, wu:fi17b11, wu:fi31c08, zgc:66494, zgc:136516Protein level used designations for CYP17A1
- cytochrome P450 17A1
- steroid 17-alpha-hydroxylase/17,20 lyase
- CYPXVII
- cytochrome P450c17
- cytochrome P450-C17
- cytochrome P450 XVIIA1
- steroid 17-alpha-monooxygenase
- steroidogenic cytochrome P450 17-hydroxylase/lyase
- Cytochrome P450 17A1
- Steroid 17-alpha-hydroxylase/17,20 lyase
- cytochrome P450 steroid 17-alpha-hydroxylase/17,20 lyase
- cytochrome P450, family 17, subfamily A, polypeptide 1
- 17-alpha-hydroxyprogesterone aldolase
- 17-alpha-hydroxylase cytochrome P450
- cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia
- cytochrome p450 XVIIA1
- cytochrome P450 steroid 17alpha-hydroxylase/17,20 lyase
- cytochrome P450, subfamily XVII
- steroid 17-alpha-hydroxylase
- cytochrome P450, 17
- cytochrome P450, 17a1
- steroid 17-alpha hydroxylase
- Cytochrome P450, subfamily XVII
- P450-C17
- P45017alpha
- P450c17
- cytochrome P450, subfamily 17
- cytochrome P450 17 alpha-hydroxylase
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