CYP11B2 Products
(Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))
Categories
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008].
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Featured CYP11B2 Categories
CYP11B2 Antibodies
High quality antibodies with extensive validation data.
CYP11B2 ELISA Kits
Reliable ELISA kits for a wide range of species.
CYP11B2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CYP11B2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN1679468
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), FACS
Validations
- (4)
Cat. No.
ABIN655163
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (3)
Cat. No.
ABIN7257862
Quantity
200 μL
Datasheet
Datasheet
Recommended CYP11B2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955237
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955238
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Sandwich ELISA
Validations
Cat. No.
ABIN424543
Quantity
96 tests
Datasheet
Datasheet
Recommended CYP11B2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7392893
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN5623846
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CYP11B2 products
: "The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion." in: JCI insight, Vol. 2, Issue 23, (2019) (PubMed).: "[Differences in adrenal steroid hormones production in pubertal rats exposed to low doses of endocrine disruptor DDT during prenatal and postnatal development]." in: Biomeditsinskaia khimiia, Vol. 63, Issue 4, pp. 306-311, (2018) (PubMed).
: "Regulation of CYP11B1 and CYP11B2 steroidogenic genes by hypoxia-inducible miR-10b in H295R cells." in: Marine pollution bulletin, Vol. 85, Issue 2, pp. 344-51, (2014) (PubMed).
: "Isoform-specific monoclonal antibodies against 3β-hydroxysteroid dehydrogenase/isomerase family provide markers for subclassification of human primary aldosteronism." in: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 2, pp. E257-62, (2014) (PubMed).
: "Structural insights into aldosterone synthase substrate specificity and targeted inhibition." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 2, pp. 315-24, (2013) (PubMed).
: "The renin-angiotensin-aldosterone system in cerebral small vessel disease." in: Journal of neurology, Vol. 255, Issue 7, pp. 993-1000, (2008) (PubMed).
Synonyms and alternative names related to CYP11B2
cytochrome P450 family 11 subfamily B member 2 (CYP11B2), cytochrome P450, family 11, subfamily b, polypeptide 2 (Cyp11b2), aldosterone synthase (Cyp11b2), cytochrome P450, family 11, subfamily B, polypeptide 2 (CYP11B2), cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2 (CYP11B2), ALDOS, Cp45as, CPN2, Cpn2, CYP11B, Cyp11b, Cyp11b-2, Cyp11b3, CYP11BL, CYPXIB2, P-450C18, P450aldo, P450C18, RNCP45ASProtein level used designations for CYP11B2
- aldosterone synthase
- aldosterone-synthesizing enzyme
- cytochrome P-450Aldo
- cytochrome P-450C18
- cytochrome P450 11B2, mitochondrial
- cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2
- mitochondrial cytochrome P450, family 11, subfamily B, polypeptide 2
- steroid 11-beta-monooxygenase
- steroid 11-beta/18-hydroxylase
- steroid 18-hydroxylase, aldosterone synthase, P450C18, P450aldo
- CYPXIB2
- cytochrome P450C11
- steroid 11-beta-hydroxylase
- steroid-11-beta-hydroxylase
- CYPXIB3
- Cytochrome P450 subfamily XIB polypeptide 2 (aldosterone synthase)
- Cytochrome P450, subfamily XIB, polypeptide 2 (aldosterone synthase)
- P450-Aldo-1
- P450-Aldo-2
- cytochrome P450 11B3, mitochondrial
- cytochrome P450, subfamily 11B, polypeptide 2
- cytochrome P450-Aldo-1
- cytochrome P450-Aldo-2
- mitochondrial cytochrome P450 11B2
- cytochrome P450, family 11, subfamily B, polypeptide 2
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