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CYP11B1 Products

(Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))

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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008].

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Featured CYP11B1 Categories

CYP11B1 Antibodies

High quality antibodies with extensive validation data.

CYP11B1 ELISA Kits

Reliable ELISA kits for a wide range of species.

CYP11B1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CYP11B1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7435544
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (p), IF (cc), IHC (fro), IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN750823
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN6746765
Quantity 100 μL
Datasheet Datasheet

Recommended CYP11B1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966230
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955235
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955236
Quantity 96 tests
Datasheet Datasheet

Recommended CYP11B1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350927
Quantity 25 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7407919
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7407916
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CYP11B1 products

Tyczewska, Rucinski, Ziolkowska, Trejter, Szyszka, Malendowicz: "Expression of selected genes involved in steroidogenesis in the course of enucleation-induced rat adrenal regeneration." in: International journal of molecular medicine, Vol. 33, Issue 3, pp. 613-23, (2014) (PubMed).

Strushkevich, Gilep, Shen, Arrowsmith, Edwards, Usanov, Park: "Structural insights into aldosterone synthase substrate specificity and targeted inhibition." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 2, pp. 315-24, (2013) (PubMed).

Miyata, Kudo, Lee, Yang, Gelboin, Fernandez-Salguero, Kimura, Gonzalez: "Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene." in: The Journal of biological chemistry, Vol. 274, Issue 34, pp. 23963-8, (1999) (PubMed).

Zhu, von Dippe, Xing, Levy: "Membrane topology and cell surface targeting of microsomal epoxide hydrolase. Evidence for multiple topological orientations." in: The Journal of biological chemistry, Vol. 274, Issue 39, pp. 27898-904, (1999) (PubMed).

Hassett, Aicher, Sidhu, Omiecinski: "Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants." in: Human molecular genetics, Vol. 3, Issue 3, pp. 421-8, (1994) (PubMed).

Synonyms and alternative names related to CYP11B1

cytochrome P450, family 11, subfamily B, polypeptide 1 (CYP11B1), cytochrome P450 family 11 subfamily B member 1 (CYP11B1), cytochrome P450, family 11, subfamily b, polypeptide 1 (Cyp11b1), cytochrome P450, subfamily XI B, polypeptide 1 (CYP11B1), AA389061, Cp11ba, CPN1, CYP11B, Cyp11b, Cyp11b-1, FHI, P450C11, P450c11, RATCP11BA

Protein level used designations for CYP11B1

  • cytochrome P450 11B1, mitochondrial
  • CYPXIB1
  • cytochrome P-450c11
  • cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1
  • cytochrome P450C11
  • cytochrome p450 XIB1
  • steroid 11-beta-hydroxylase
  • steroid 11-beta-monooxygenase
  • steroid-11-beta-hydroxylase
  • Cytochrome P450, subfamily XIB, polypeptide 1 (steroid 11-beta-hydroxylase)
  • P450(11 beta)-DS
  • P450C11
  • aldosterone synthase
  • cytochrome P450(11 beta)-DS
  • cytochrome P450, subfamily 11B, polypeptide 1
  • 11-beta-hydroxylase
  • 11beta-hydroxylase
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