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CYLD Products

(Cylindromatosis (Turban Tumor Syndrome) (CYLD))
This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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Featured CYLD Categories

CYLD Antibodies

High quality antibodies with extensive validation data.

CYLD ELISA Kits

Reliable ELISA kits for a wide range of species.

CYLD Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CYLD Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7434896
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (6)
Cat. No. ABIN1679467
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ICC, IF, IHC (p)
Validations
  • (5)
Cat. No. ABIN2854660
Quantity 100 μL
Datasheet Datasheet

Recommended CYLD ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955171
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1165001
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1165002
Quantity 96 tests
Datasheet Datasheet

Recommended CYLD Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122546
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350917
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2712747
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our CYLD products

Wu, Mu, Gao, Wang, Sy, Li: "Prion protein is required for tumor necrosis factor α (TNFα)-triggered nuclear factor κB (NF-κB) signaling and cytokine production." in: The Journal of biological chemistry, Vol. 292, Issue 46, pp. 18747-18759, (2017) (PubMed).

Thein, Tao-Cheng, Li, Bayer, Reese, Dosemeci: "CaMKII mediates recruitment and activation of the deubiquitinase CYLD at the postsynaptic density." in: PLoS ONE, Vol. 9, Issue 3, pp. e91312, (2014) (PubMed).

Moranta, Regueiro, March, Llobet, Margareto, Larrarte, Larrate, Garmendia, Bengoechea: "Klebsiella pneumoniae capsule polysaccharide impedes the expression of beta-defensins by airway epithelial cells." in: Infection and immunity, Vol. 78, Issue 3, pp. 1135-46, (2010) (PubMed).

Massoumi, Chmielarska, Hennecke, Pfeifer, Fässler: "Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling." in: Cell, Vol. 125, Issue 4, pp. 665-77, (2006) (PubMed).

Hellerbrand, Bumes, Bataille, Dietmaier, Massoumi, Bosserhoff: "Reduced expression of CYLD in human colon and hepatocellular carcinomas." in: Carcinogenesis, Vol. 28, Issue 1, pp. 21-7, (2006) (PubMed).

Regamey, Hohl, Liu, Roger, Kogerman, Toftgard, Huber: "The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor." in: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1959-64, (2003) (PubMed).

Synonyms and alternative names related to CYLD

CYLD lysine 63 deubiquitinase (CYLD), CYLD lysine 63 deubiquitinase (Cyld), cylindromatosis (turban tumor syndrome), a (cylda), 2010013M14Rik, 2900009M21Rik, BRSS, C130039D01Rik, CDMT, cyld, CYLD1, CYLDI, EAC, LRRGT00003, MFT, MFT1, mKIAA0849, Rp1, Rp1h, SBS, TEM, USPL2

Protein level used designations for CYLD

  • deubiquitinating enzyme CYLD
  • probable ubiquitin carboxyl-terminal hydrolase CYLD
  • ubiquitin carboxyl-terminal hydrolase CYLD
  • ubiquitin specific peptidase like 2
  • ubiquitin thioesterase CYLD
  • ubiquitin thiolesterase CYLD
  • ubiquitin-specific-processing protease CYLD
  • cylindromatosis (turban tumor syndrome)
  • probable ubiquitin carboxyl-terminal hydrolase CYLD-like
  • retinitis pigmentosa 1 homolog
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