Cyclin D3 Products
(Cyclin D3 (CCND3))
Categories
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
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Featured Cyclin D3 Categories
Cyclin D3 Antibodies
High quality antibodies with extensive validation data.
Cyclin D3 ELISA Kits
Reliable ELISA kits for a wide range of species.
Cyclin D3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Cyclin D3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IP, IF
Validations
- (5)
Cat. No.
ABIN7153394
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rabbit
Application
WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro)
Validations
- (1)
- (4)
Cat. No.
ABIN671571
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, ICC, IF
Validations
- (4)
Cat. No.
ABIN6255654
Quantity
100 μL
Datasheet
Datasheet
Recommended Cyclin D3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966160
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955151
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1114483
Quantity
96 tests
Datasheet
Datasheet
Recommended Cyclin D3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348451
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348453
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505171
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Cyclin D3 products
: "Genistein protects hematopoietic stem cells against G-CSF-induced DNA damage." in: Cancer prevention research (Philadelphia, Pa.), Vol. 7, Issue 5, pp. 534-44, (2014) (PubMed).: "CKbeta8/CCL23 and its isoform CKbeta8-1 induce up-regulation of cyclins via the G(i)/G(o) protein/PLC/PKCdelta/ERK leading to cell-cycle progression." in: Cytokine, Vol. 50, Issue 1, pp. 42-9, (2010) (PubMed).
: "Cyclin D3 is dispensable for human diffuse large B-cell lymphoma survival and growth: evidence for redundancy with cyclin E." in: Cell cycle (Georgetown, Tex.), Vol. 9, Issue 4, pp. 820-8, (2010) (PubMed).
: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
: "Genome-wide association study of hematological and biochemical traits in a Japanese population." in: Nature genetics, Vol. 42, Issue 3, pp. 210-5, (2010) (PubMed).
: "Immunoreactivity of p27(Kip1), cyclin D3, and Ki67 in conventional renal cell carcinoma." in: International urology and nephrology, Vol. 41, Issue 2, pp. 243-9, (2009) (PubMed).
: "Translocations targeting CCND2, CCND3, and MYCN do occur in t(11;14)-negative mantle cell lymphomas." in: Blood, Vol. 111, Issue 12, pp. 5683-90, (2008) (PubMed).
: "Overexpression of cyclin D1, D3, and p21 in an infantile renal carcinoma with Xp11.2 TFE3-gene fusion." in: Pathology, research and practice, Vol. 204, Issue 8, pp. 589-97, (2008) (PubMed).
: "Expression of p27((Kip1)), cyclin D3 and Ki67 in BPH, prostate cancer and hormone-treated prostate cancer cells." in: International urology and nephrology, Vol. 40, Issue 4, pp. 953-9, (2008) (PubMed).
: "L-arginine availability regulates T-lymphocyte cell-cycle progression." in: Blood, Vol. 109, Issue 4, pp. 1568-73, (2007) (PubMed).
Synonyms and alternative names related to Cyclin D3
cyclin D3 (ccnd3), cyclin D3 (CCND3), cyclin D3 (Ccnd3), 9230106B05Rik, AA682053, AL024085, AW146355, C78795, CCND3, zgc:103502Protein level used designations for Cyclin D3
- cyclin D3
- G1/S-specific cyclin-D3
- D3-type cyclin
- G1/S-specific cyclin D3
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