Cyclin A1 Products
(Cyclin A1 (CCNA1))
Categories
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured Cyclin A1 Categories
Cyclin A1 Antibodies
High quality antibodies with extensive validation data.
Cyclin A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Cyclin A1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Cyclin A1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7180926
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
Cat. No.
ABIN6261140
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat, Sheep
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (4)
- (2)
Cat. No.
ABIN714026
Quantity
100 μL
Datasheet
Datasheet
Recommended Cyclin A1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955144
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN4993357
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN4993356
Quantity
96 tests
Datasheet
Datasheet
Recommended Cyclin A1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122517
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348428
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7424668
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Cyclin A1 products
: "Daidzein and Chicory Extract Arrest the Cell Cycle via Inhibition of Cyclin D/CDK4 and Cyclin A/CDK2 Gene Expression in Hepatocellular Carcinoma." in: Recent patents on anti-cancer drug discovery, Vol. 18, Issue 2, pp. 187-199, (2023) (PubMed).: "Inhibition of peripubertal sheep mammary gland development by cysteamine through reducing progesterone and growth factor production." in: Theriogenology, Vol. 89, pp. 280-288, (2017) (PubMed).
: "STAT3 stimulates adipogenic stem cell proliferation and cooperates with HMGA2 during the early stage of differentiation to promote adipogenesis." in: Biochemical and biophysical research communications, Vol. 482, Issue 4, pp. 1360-1366, (2017) (PubMed).
: "Autocrine fibronectin from differentiating mesenchymal stem cells induces the neurite elongation in vitro and promotes nerve fiber regeneration in transected spinal cord injury." in: Journal of biomedical materials research. Part A, Vol. 104, Issue 8, pp. 1902-11, (2017) (PubMed).
: "Sundew plant, a potential source of anti-inflammatory agents, selectively induces G2/M arrest and apoptosis in MCF-7 cells through upregulation of p53 and Bax/Bcl-2 ratio." in: Cell death discovery, Vol. 2, pp. 15062, (2016) (PubMed).
: "Overexpression of miR-30a in lung adenocarcinoma A549 cell line inhibits migration and invasion via targeting EYA2." in: Acta biochimica et biophysica Sinica, Vol. 48, Issue 3, pp. 220-8, (2016) (PubMed).
: "Studying the relationship between cell cycle and Alzheimer's disease by gold nanoparticle probes." in: Analytical biochemistry, Vol. 489, pp. 32-7, (2015) (PubMed).
: "An antioxidant extract of tropical lichen, Parmotrema reticulatum, induces cell cycle arrest and apoptosis in breast carcinoma cell line MCF-7." in: PLoS ONE, Vol. 8, Issue 12, pp. e82293, (2013) (PubMed).
: "Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen." in: Blood, Vol. 119, Issue 23, pp. 5492-501, (2012) (PubMed).
: "Characterization of a second human cyclin A that is highly expressed in testis and in several leukemic cell lines." in: Cancer research, Vol. 57, Issue 5, pp. 913-20, (1997) (PubMed).
Synonyms and alternative names related to Cyclin A1
cyclin A1 (CCNA1), cyclin A1 (ccna1), cyclin A1 L homeolog (ccna1.L), CYCLIN A1;2 (CYCA1;2), cyclin A1 (Ccna1), cyclin A1 S homeolog (ccna1.S), CCNA1, ccna1, cyclin-A1, Cyclin-A1, cyclin-A1-2, fd14f08, MGC81965, MGC132235, wu:fd14f08, wu:fi20d12, zgc:111869Protein level used designations for Cyclin A1
- cyclin-A1
- cyclin A1
- cyclin-A1-like
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