CYBB Products
(Cytochrome B-245, beta Polypeptide (CYBB))
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Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase\; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008].
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CYBB Antibodies
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CYBB ELISA Kits
Reliable ELISA kits for a wide range of species.
CYBB Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CYBB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Chicken, Human, Mouse, Rabbit, Rat
Application
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (6)
- (5)
Cat. No.
ABIN750688
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN3022300
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7149094
Quantity
100 μg
Datasheet
Datasheet
Recommended CYBB ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955210
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955211
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966209
Quantity
96 tests
Datasheet
Datasheet
Recommended CYBB Proteins
Latest Publications for our CYBB products
: "Breaking the vicious loop between inflammation, oxidative stress and coagulation, a novel anti-thrombus insight of nattokinase by inhibiting LPS-induced inflammation and oxidative stress." in: Redox biology, Vol. 32, pp. 101500, (2020) (PubMed).: "Hydrogen Sulfide Donor NaHS Improves Metabolism and Reduces Muscle Atrophy in Type 2 Diabetes: Implication for Understanding Sarcopenic Pathophysiology." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 6825452, (2019) (PubMed).
: "Maternal inflammation activated ROS-p38 MAPK predisposes offspring to heart damages caused by isoproterenol via augmenting ROS generation." in: Scientific reports, Vol. 6, pp. 30146, (2018) (PubMed).
: "CRISPR/Cas9-mediated ASXL1 mutations in U937 cells disrupt myeloid differentiation." in: International journal of oncology, Vol. 52, Issue 4, pp. 1209-1223, (2018) (PubMed).
: "Taurine Attenuates Calpain-2 Induction and a Series of Cell Damage via Suppression of NOX-Derived ROS in ARPE-19 Cells." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 4596746, (2018) (PubMed).
: "Inhibition of leukotriene B4 synthesis protects against early brain injury possibly via reducing the neutrophil-generated inflammatory response and oxidative stress after subarachnoid hemorrhage in ..." in: Behavioural brain research, Vol. 339, pp. 19-27, (2017) (PubMed).
: "Chronic cerebral hypoperfusion alters amyloid-β peptide pools leading to cerebral amyloid angiopathy, microinfarcts and haemorrhages in Tg-SwDI mice." in: Clinical science (London, England : 1979), Vol. 131, Issue 16, pp. 2109-2123, (2017) (PubMed).
: "Graviola inhibits hypoxia-induced NADPH oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity." in: Scientific reports, Vol. 6, pp. 23135, (2017) (PubMed).
: "Obligatory role for GPER in cardiovascular aging and disease." in: Science signaling, Vol. 9, Issue 452, pp. ra105, (2017) (PubMed).
: "Oxidative activation of CaMKIIδ in acute myocardial ischemia/reperfusion injury: A role of angiotensin AT1 receptor-NOX2 signaling axis." in: European journal of pharmacology, Vol. 771, pp. 114-22, (2016) (PubMed).
Synonyms and alternative names related to CYBB
cytochrome b-245, beta polypeptide (chronic granulomatous disease) (cybb), cytochrome b-245, beta polypeptide (cybb), cytochrome b-245 heavy chain (CYBB), cytochrome b-245, beta polypeptide L homeolog (cybb.L), cytochrome b-245, beta polypeptide (CYBB), cytochrome b-245 beta polypeptide (CYBB), cytochrome b-245 beta chain (CYBB), cytochrome b-245, beta polypeptide (Cybb), cytochrome b-245 beta chain (Cybb), cytochrome b-245, beta polypeptide (chronic granulomatous disease) (CYBB), NADPH oxidase heavy chain subunit (GP91-PHOX), AMCBX2, C88302, cgd, CGD, Cgd, CGD91-phox, cybb, CYBB, Cyd, gp91-1, GP91-1, gp91-phox, GP91-PHOX, Gp91-phox, gp91phox, GP91PHOX, NOX1, nox2, NOX2, Nox2, p91-PHOX, zgc:64144Protein level used designations for CYBB
- cytochrome b-245, beta polypeptide
- gp91
- NADPH oxidase 2
- cytochrome b-245, beta polypeptide (chronic granulomatous disease)
- Cytochrome b-245 heavy chain
- NADPH oxidase heavy chain subunit
- NADPH oxidase 1
- NADPH oxidase flavocytochrome b subunit
- cytochrome b-245 heavy chain
- gp91-phox
- CGD91-phox
- cytochrome b(558) subunit beta
- cytochrome b558 subunit beta
- heme-binding membrane glycoprotein gp91phox
- neutrophil cytochrome b 91 kDa polypeptide
- p22 phagocyte B-cytochrome
- superoxide-generating NADPH oxidase heavy chain subunit
- gp91-1
- endothelial type gp91-phox
- predicted NADPH oxidase-2
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