CYB5R3 Products
(Cytochrome B5 Reductase 3 (CYB5R3))
Categories
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010].
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Featured CYB5R3 Categories
CYB5R3 Antibodies
High quality antibodies with extensive validation data.
CYB5R3 ELISA Kits
Reliable ELISA kits for a wide range of species.
CYB5R3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CYB5R3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
Cat. No.
ABIN560603
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7160982
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN514976
Quantity
50 μg
Datasheet
Datasheet
Recommended CYB5R3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966213
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966212
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN813300
Quantity
96 tests
Datasheet
Datasheet
Recommended CYB5R3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1350883
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122569
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350885
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our CYB5R3 products
: "Enhanced DNA adduct formation by benzo[a]pyrene in human liver cells lacking cytochrome P450 oxidoreductase." in: Mutation research, Vol. 852, pp. 503162, (2020) (PubMed).: "Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine." in: Toxicology and applied pharmacology, Vol. 366, pp. 64-74, (2019) (PubMed).
: "Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) mice." in: Archives of toxicology, Vol. 92, Issue 4, pp. 1625-1638, (2019) (PubMed).
: "The N-reductive system composed of mitochondrial amidoxime reducing component (mARC), cytochrome b5 (CYB5B) and cytochrome b5 reductase (CYB5R) is regulated by fasting and high fat diet in mice." in: PloS one, Vol. 9, Issue 8, pp. e105371, (2014) (PubMed).
: "Identification of the missing component in the mitochondrial benzamidoxime prodrug-converting system as a novel molybdenum enzyme." in: The Journal of biological chemistry, Vol. 281, Issue 46, pp. 34796-802, (2006) (PubMed).
: "RhoB regulates endosome transport by promoting actin assembly on endosomal membranes through Dia1." in: Journal of cell science, Vol. 118, Issue Pt 12, pp. 2661-70, (2005) (PubMed).
Synonyms and alternative names related to CYB5R3
cytochrome b5 reductase 3 (CYB5R3), cytochrome b5 reductase 3 (Cyb5r3), cytochrome b5 reductase 3 (cyb5r3), cytochrome b5 reductase 3 L homeolog (cyb5r3.L), NADH-cytochrome b5 reductase (CNM00240), NADH-cytochrome b5 reductase (Tb11.47.0018), NADH-cytochrome b5 reductase (cyb5r1), 0610016L08Rik, 2500002N19Rik, B5R, C85115, CB5R, DDBDRAFT_0218707, DDBDRAFT_0266821, DDB_0218707, DDB_0266821, Dia-1, DIA1, Dia1, dia1, fc32h03, Nadhcb5, RNNADHCB5, WU:AL591952.1-001, WU:AL591952.1-002, WU:AL591952.1-003, WU:Cyb5r3, wu:fc32h03, zgc:77071Protein level used designations for CYB5R3
- NADH-cytochrome b5 reductase 3
- NADH-cytochrome b5 reductase 3 membrane-bound form
- NADH-cytochrome b5 reductase 3 soluble form
- diaphorase-1
- B5R
- Diaphorase (NADH) (cytochrome b-5 reductase)
- diaphorase 1
- diaphorase 1 (NADH)
- NADH-cytochrome b5 reductase
- cytochrome b5 reductase 3
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