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CXCL12 Products

(Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010].

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Featured CXCL12 Categories

CXCL12 Antibodies

High quality antibodies with extensive validation data.

CXCL12 ELISA Kits

Reliable ELISA kits for a wide range of species.

CXCL12 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CXCL12 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7008123
Quantity 60 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7431116
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN6139271
Quantity 100 μL
Datasheet Datasheet

Recommended CXCL12 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (16)
  • (4)
Cat. No. ABIN6730881
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (10)
  • (1)
Cat. No. ABIN6954670
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
  • (1)
Cat. No. ABIN6954668
Quantity 96 tests
Datasheet Datasheet

Recommended CXCL12 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (3)
Cat. No. ABIN6239854
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122328
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122325
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our CXCL12 products

John, Poos, Brobeil, Schinke, Huhn, Prokoph, Lutz, Wagner, Zangari, Tirier, Mallm, Schumacher, Vonficht, Solé-Boldo, Quick, Steiger, Przybilla, Bauer, Baumann, Hemmer, Rehnitz, Lückerath, Sachpekidis et al.: "Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level. ..." in: Nature communications, Vol. 14, Issue 1, pp. 5011, (2023) (PubMed).

Chen, Li, Chen, Han, Li, Guo, Liu, Xiao: "Enhanced recruitment and hematopoietic reconstitution of bone marrow-derived mesenchymal stem cells in bone marrow failure by the SDF-1/CXCR4." in: Journal of tissue engineering and regenerative medicine, Vol. 14, Issue 9, pp. 1250-1260, (2020) (PubMed).

Ji, Yao, Zhao, Zhai, Weng, He: "Extracellular ubiquitin levels are increased in coronary heart disease and associated with the severity of the disease." in: Scandinavian journal of clinical and laboratory investigation, Vol. 80, Issue 3, pp. 256-264, (2020) (PubMed).

Zhuang, Yi, Chen, Kang, Chen, Chen, Cui, Chang, Ye, Ni, Wang, Du, Li, Liu, Jian, Li, Gao, Li, Li: "Intracellular virus sensor MDA5 exacerbates vitiligo by inducing the secretion of chemokines in keratinocytes under virus invasion." in: Cell death & disease, Vol. 11, Issue 6, pp. 453, (2020) (PubMed).

Golle, Gerth, Beul, Heitplatz, Barth, Fobker, Pavenstädt, Di Marco, Brand: "Bone marrow-derived cells and their conditioned medium induce microvascular repair in uremic rats by stimulation of endogenous repair mechanisms." in: Scientific reports, Vol. 7, Issue 1, pp. 9444, (2019) (PubMed).

Abdelaal, Elhefnawy, Abdulmonem, Sayed, Saleh, Saleh: "Evaluation of the expression of the stromal cell-derived factor-1 alpha (CXCL 12) in psoriatic patients after treatment with Methotrexate." in: Journal of cosmetic dermatology, (2019) (PubMed).

Visweshwaran, Maritzen: "A simple 3D cellular chemotaxis assay and analysis workflow suitable for a wide range of migrating cells." in: MethodsX, Vol. 6, pp. 2807-2821, (2019) (PubMed).

Wu, Cao, Liu, Zheng, Jiao, Zeng, Wang, Kaplan, Jiang: "Functionalization of Silk Fibroin Electrospun Scaffolds via BMSC Affinity Peptide Grafting through Oxidative Self-Polymerization of Dopamine for Bone Regeneration." in: ACS applied materials & interfaces, Vol. 11, Issue 9, pp. 8878-8895, (2019) (PubMed).

Ying, Wen, Pei, Su, Ruan: "Stromal cell-derived factor-1α promotes recruitment and differentiation of nucleus pulposus-derived stem cells." in: World journal of stem cells, Vol. 11, Issue 3, pp. 196-211, (2019) (PubMed).

Li, Xu, Qian: "c-Kit-Positive Adipose Tissue-Derived Mesenchymal Stem Cells Promote the Growth and Angiogenesis of Breast Cancer." in: BioMed research international, Vol. 2017, pp. 7407168, (2018) (PubMed).

Synonyms and alternative names related to CXCL12

C-X-C motif chemokine ligand 12 (CXCL12), C-X-C motif chemokine ligand 12 (cxcl12), C-X-C motif chemokine ligand 1 (Cxcl1), chemokine (C-X-C motif) ligand 12 (Cxcl12), C-X-C motif chemokine ligand 12 (Cxcl12), chemokine (C-X-C motif) ligand 1 (Cxcl1), C-X-C motif chemokine ligand 12 L homeolog (cxcl12.L), chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) (cxcl12a), CINC-1, cxcl12, Fsp, gro, Gro1, IRH, KC, Mgsa, N51, PBSF, Pbsf, Scyb1, SCYB12, Scyb12, sdf-1, SDF-1, sdf-1a, SDF1, Sdf1, sdf1, sdf1a, TLSF, Tlsf, TPAR1, Tpar1, wu:fa55e10, wu:fc16h12, wu:fj84c02, xSDF-1

Protein level used designations for CXCL12

  • intercrine reduced in hepatomas
  • pre-B cell growth-stimulating factor
  • stromal cell-derived factor 1
  • chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)
  • chemokine CXCL12/SDF-1ALPHA
  • stromal cell-derived factor 1 isoform alpha
  • stromal cell-derived factor 1 isoform gamma
  • CXCL12
  • C-X-C motif chemokine 1
  • chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
  • cytokine-induced neutrophil chemoattractant 1
  • gro
  • growth-regulated alpha protein
  • platelet-derived growth factor-inducible protein KC
  • 12-O-tetradecanoylphorbol 13-acetate repressed protein 1
  • pre-B-cell growth-stimulating factor
  • thymic lymphoma cell-stimulating factor
  • SDF-1 gamma
  • Stromal cell-derived factor 1
  • stromal cell-derived factor-1 gamma
  • GRO1 oncogene
  • KC/GR)-alpha
  • KC/GRO-alpha
  • alpha-chemokine
  • secretory protein N51
  • C-X-C motif chemokine 12
  • stromal-derived factor 1
  • chemokine ligand 12b
  • stromal cell derived factor 1
  • stromal cell-derived factor-1 beta
  • CXC chemokine
  • CXCL12 chemokine
  • chemokine ligand 12
  • unm t30516
  • unm_t30516
  • chemokine (C-X-C motif) ligand 12
  • stromal cell-derived factor 1-like protein
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