Cullin 4B Products
(Cullin 4B (CUL4B))
Categories
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured Cullin 4B Categories
Cullin 4B Antibodies
High quality antibodies with extensive validation data.
Cullin 4B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Cullin 4B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (6)
Cat. No.
ABIN3187726
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Mouse
Application
WB, IHC, IHC (p)
Validations
- (6)
Cat. No.
ABIN1490724
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN6139255
Quantity
100 μL
Datasheet
Datasheet
Recommended Cullin 4B ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6215470
Quantity
96 tests
Datasheet
Datasheet
Recommended Cullin 4B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350769
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3091967
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3130673
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Cullin 4B products
: "Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase." in: Cancer cell, Vol. 18, Issue 4, pp. 329-40, (2010) (PubMed).: "Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks." in: Human molecular genetics, Vol. 19, Issue 7, pp. 1324-34, (2010) (PubMed).
: "Cullins in human intra-uterine growth restriction: expressional and epigenetic alterations." in: Placenta, Vol. 31, Issue 2, pp. 151-7, (2010) (PubMed).
: "A novel nonsense mutation in CUL4B gene in three brothers with X-linked mental retardation syndrome." in: Clinical genetics, Vol. 77, Issue 2, pp. 141-4, (2010) (PubMed).
: "CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation." in: Molecular cell, Vol. 40, Issue 1, pp. 9-21, (2010) (PubMed).
: "Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, ..." in: American journal of human genetics, Vol. 80, Issue 2, pp. 345-52, (2007) (PubMed).
: "Mutation in CUL4B, which encodes a member of cullin-RING ubiquitin ligase complex, causes X-linked mental retardation." in: American journal of human genetics, Vol. 80, Issue 3, pp. 561-6, (2007) (PubMed).
: "Dioxin receptor is a ligand-dependent E3 ubiquitin ligase." in: Nature, Vol. 446, Issue 7135, pp. 562-6, (2007) (PubMed).
Synonyms and alternative names related to Cullin 4B
cullin 4B (CUL4B), cullin 4B (Cul4b), cullin 4B (cul4b), cullin 4B S homeolog (cul4b.S), cullin 4B (Tb927.3.1290), 2700050M05Rik, AA409770, CUL-4B, im:7140950, im:7150765, MGC115611, mKIAA0695, MRXHF2, mrxhf2, MRXS15, MRXSC, mrxsc, RGD1564494, SFM2, sfm2, Tb03.1J15.620Protein level used designations for Cullin 4B
- CUL-4B
- cullin-4B
- cullin 4B
- cullin-4B-like
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