Cullin 4A Products
(Cullin 4A (CUL4A))
Categories
CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al., 2009 [PubMed 19481525]).[supplied by OMIM, Oct 2009].
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Featured Cullin 4A Categories
Cullin 4A Antibodies
High quality antibodies with extensive validation data.
Cullin 4A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Cullin 4A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (4)
Cat. No.
ABIN521910
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP
Validations
- (4)
Cat. No.
ABIN3016906
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (3)
Cat. No.
ABIN657794
Quantity
400 μL
Datasheet
Datasheet
Recommended Cullin 4A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6203592
Quantity
96 tests
Datasheet
Datasheet
Recommended Cullin 4A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350765
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350767
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3091948
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Cullin 4A products
: "CUL4A promotes cell invasion in gastric cancer by activating the NF-κB signaling pathway." in: Biologics : targets & therapy, Vol. 11, pp. 45-53, (2018) (PubMed).: "Recurrent Amplification at 13q34 Targets at CUL4A, IRS2, and TFDP1 As an Independent Adverse Prognosticator in Intrahepatic Cholangiocarcinoma." in: PLoS ONE, Vol. 10, Issue 12, pp. e0145388, (2015) (PubMed).
: "Efficient parvovirus replication requires CRL4Cdt2-targeted depletion of p21 to prevent its inhibitory interaction with PCNA." in: PLoS pathogens, Vol. 10, Issue 4, pp. e1004055, (2014) (PubMed).
: "Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis." in: Cell research, Vol. 22, Issue 8, pp. 1258-69, (2012) (PubMed).
: "Cullin-4A·DNA damage-binding protein 1 E3 ligase complex targets tumor suppressor RASSF1A for degradation during mitosis." in: The Journal of biological chemistry, Vol. 286, Issue 9, pp. 6971-8, (2011) (PubMed).
: "The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation." in: Molecular and cellular biology, Vol. 31, Issue 22, pp. 4513-23, (2011) (PubMed).
: "DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress." in: Cancer research, Vol. 69, Issue 6, pp. 2630-7, (2009) (PubMed).
: "PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex." in: Genes & development, Vol. 22, Issue 18, pp. 2496-506, (2008) (PubMed).
: "CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation." in: The Journal of biological chemistry, Vol. 283, Issue 43, pp. 29045-52, (2008) (PubMed).
: "VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation." in: Oncogene, Vol. 27, Issue 29, pp. 4056-64, (2008) (PubMed).
Synonyms and alternative names related to Cullin 4A
cullin 4A (CUL4A), cullin 4A (cul4a), cullin 4A (Cul4a), 2810470J21Rik, AW495282, CUL4A, RGD1563853, zgc:64071Protein level used designations for Cullin 4A
- cullin 4A
- cullin-4A-like
- CUL-4A
- cullin-4A
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