Cullin 3 Products
(Cullin 3 (CUL3))
Categories
This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].
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Featured Cullin 3 Categories
Cullin 3 Antibodies
High quality antibodies with extensive validation data.
Cullin 3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Cullin 3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN7266543
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (1)
- (2)
Cat. No.
ABIN705296
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7234943
Quantity
200 μL
Datasheet
Datasheet
Recommended Cullin 3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6210015
Quantity
96 tests
Datasheet
Datasheet
Recommended Cullin 3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1787157
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350763
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2712631
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our Cullin 3 products
: "Rotavirus NSP1 Associates with Components of the Cullin RING Ligase Family of E3 Ubiquitin Ligases." in: Journal of virology, Vol. 90, Issue 13, pp. 6036-48, (2016) (PubMed).: "Tetrachlorobenzoquinone activates nrf2 signaling by keap1 cross-linking and ubiquitin translocation but not keap1-cullin3 complex dissociation." in: Chemical research in toxicology, Vol. 28, Issue 4, pp. 765-74, (2015) (PubMed).
: "Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 5, pp. E260-7, (2012) (PubMed).
: "Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1." in: Oncogene, Vol. 30, Issue 42, pp. 4350-64, (2011) (PubMed).
: "Sporadic paediatric and adult Burkitt lymphomas share similar phenotypic and genotypic features." in: Histopathology, Vol. 52, Issue 4, pp. 427-35, (2008) (PubMed).
: "TBP-interacting protein 120B (TIP120B)/cullin-associated and neddylation-dissociated 2 (CAND2) inhibits SCF-dependent ubiquitination of myogenin and accelerates myogenic differentiation." in: The Journal of biological chemistry, Vol. 282, Issue 12, pp. 9017-28, (2007) (PubMed).
: "A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells." in: Developmental cell, Vol. 12, Issue 6, pp. 887-900, (2007) (PubMed).
: "Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases." in: Nature cell biology, Vol. 5, Issue 11, pp. 1001-7, (2003) (PubMed).
: "Covalent modification of all members of human cullin family proteins by NEDD8." in: Oncogene, Vol. 18, Issue 48, pp. 6829-34, (2000) (PubMed).
: "Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells." in: Genes & development, Vol. 13, Issue 18, pp. 2375-87, (1999) (PubMed).
Synonyms and alternative names related to Cullin 3
cullin 3 (CUL3), cullin 3 (cul3), cullin 3 L homeolog (cul3.L), cullin 3 S homeolog (cul3.S), cullin-3 (PTRG_11586), Cullin-3 (CUL-3) (Smp_117580), cullin 3a (cul3a), cullin 3 (Cul3), CULlin (cul-3), AI467304, ATCUL3, ATCUL3A, AW146203, CUL-3, CUL-3-A, CUL-3-B, cul3, CUL3, cul3a, CUL3A, cul3b, Cullin-3, Cullin-3-A, Cullin-3-B, cullin 3, cullin 3A, mKIAA0617, PHA2E, T24P13.25, wu:fc37e01Protein level used designations for Cullin 3
- cullin-3
- cullin-3-A
- cullin-3-B
- Cullin-3 (CUL-3)
- cullin 3
- CUL-3
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