CTSC Products
(Cathepsin C (CTSC))
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The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured CTSC Categories
CTSC Antibodies
High quality antibodies with extensive validation data.
CTSC ELISA Kits
Reliable ELISA kits for a wide range of species.
CTSC Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CTSC Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
Cat. No.
ABIN6139221
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (3)
Cat. No.
ABIN1858542
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7184675
Quantity
100 μg
Datasheet
Datasheet
Recommended CTSC ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6954450
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965506
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4882112
Quantity
96 tests
Datasheet
Datasheet
Recommended CTSC Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350706
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN4370678
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397018
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CTSC products
: "Integrating multiple 'omics' analyses identifies serological protein biomarkers for preeclampsia." in: BMC medicine, Vol. 11, pp. 236, (2014) (PubMed).: "Are proteinase 3 and cathepsin C enzymes related to pathogenesis of periodontitis?" in: BioMed research international, Vol. 2014, pp. 420830, (2014) (PubMed).
Synonyms and alternative names related to CTSC
cathepsin C (CTSC), cathepsin C L homeolog (ctsc.L), cathepsin C (ctsc), cathepsin C (TP03_0357), cathepsin C (CMU_003360), cathepsin CPC1 (CPC1), cathepsin C (NAEGRDRAFT_80477), cathepsin C (NAEGRDRAFT_37577), cathepsin C (Ctsc), cathepsin C (Smp_183330), AI047818, CATC, cb912, CPPI, DPP-I, DPP1, DPPI, HMS, ik:tdsubc_1h2, JP, JPD, MGC69126, MGC107782, PALS, PDON1, PLS, sb:cb146, wu:fb34g12, wu:fj58d01Protein level used designations for CTSC
- cathepsin J
- dipeptidyl peptidase 1
- dipeptidyl peptidase I
- dipeptidyl transferase
- dipeptidyl-peptidase I
- cathepsin C
- dipeptidyl peptidase 1 isoform a preproprotein
- DPPI
- DPP-I
- Dipeptidyl-peptidase 1
- dipeptidyl-peptidase 1
- dipeptidylpeptidase 1
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