CSTB Products
(Cystatin B (Stefin B) (CSTB))
Categories
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). [provided by RefSeq, Jul 2008].
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Featured CSTB Categories
CSTB Antibodies
High quality antibodies with extensive validation data.
CSTB ELISA Kits
Reliable ELISA kits for a wide range of species.
CSTB Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CSTB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF, IP
Validations
- (5)
Cat. No.
ABIN7148987
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (5)
Cat. No.
ABIN6261072
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (5)
Cat. No.
ABIN560509
Quantity
100 μg
Datasheet
Datasheet
Recommended CSTB ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (7)
- (1)
Cat. No.
ABIN6955179
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966192
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6973896
Quantity
96 tests
Datasheet
Datasheet
Recommended CSTB Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350601
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7400477
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7399697
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CSTB products
: "Diagnostic specificity and sensitivity of PIVKAII, GP3, CSTB, SCCA1 and HGF for the diagnosis of hepatocellular carcinoma in patients with alcoholic liver cirrhosis." in: Annals of clinical biochemistry, Vol. 55, Issue 3, pp. 355-362, (2019) (PubMed).: "Cystatin B Involvement in Synapse Physiology of Rodent Brains and Human Cerebral Organoids." in: Frontiers in molecular neuroscience, Vol. 12, pp. 195, (2019) (PubMed).
: "Cocaine potentiates cathepsin B secretion and neuronal apoptosis from HIV-infected macrophages." in: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, Vol. 9, Issue 5, pp. 703-15, (2014) (PubMed).
: "Cathepsin B and cystatin B in HIV-seropositive women are associated with infection and HIV-1-associated neurocognitive disorders." in: AIDS, Vol. 27, Issue 3, pp. 347-56, (2013) (PubMed).
: "Evaluation of serum procathepsin B, cystatin B and cystatin C as possible biomarkers of ovarian cancer." in: International journal of circumpolar health, Vol. 72, (2013) (PubMed).
: "Dysregulation of macrophage-secreted cathepsin B contributes to HIV-1-linked neuronal apoptosis." in: PLoS ONE, Vol. 7, Issue 5, pp. e36571, (2012) (PubMed).
: "Identification of cystatin SA as a novel inhibitor of acid ceramidase." in: The Journal of biological chemistry, Vol. 286, Issue 41, pp. 35624-33, (2011) (PubMed).
: "Novel cystatin B mutation and diagnostic PCR assay in an Unverricht-Lundborg progressive myoclonus epilepsy patient." in: American journal of medical genetics, Vol. 74, Issue 5, pp. 467-71, (1997) (PubMed).
: "Type B gastritis, aging, and Campylobacter pylori." in: Archives of internal medicine, Vol. 148, Issue 5, pp. 1021-2, (1988) (PubMed).
: "A possible role for endogenous prostaglandins in the electrophysiological effects of acetylstrophanthidin on isolated canine ventricular tissues." in: Circulation research, Vol. 58, Issue 4, pp. 486-94, (1986) (PubMed).
Synonyms and alternative names related to CSTB
cystatin B (CSTB), cystatin B (stefin B) (CSTB), cystatin B (Cstb), cystatin B (stefin B) (cstb), cystatin 14a, tandem duplicate 2 (cst14a.2), cystatin B (CYSB), cystatin B (cpi1), cystatin-B (LOC101123265), AA960480, ARABIDOPSIS THALIANA PHYTOCYSTATIN 6, ATCYS6, ATCYSB, CPI1, CST6, cst6, CSTB, Cyb, cystatin B, EPM1, Epm1, epm1, EPM1A, LOC100008600, LOC100136235, MGC189005, PME, pme, STFB, Stfb, stfb, ULDProtein level used designations for CSTB
- CPI-B
- cystatin-B
- liver thiol proteinase inhibitor
- cystatin B protein
- stefin-B
- cystatin B (stefin B)
- cystatin beta
- cystatin-beta
- stefin B
- stefin C
- stefin-C
- cystatin B
- Leukocyte cysteine proteinase inhibitor 1
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