CRTC1 Products
(CREB Regulated Transcription Coactivator 1 (CRTC1))
Categories
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells (By similarity). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons.
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Featured CRTC1 Categories
CRTC1 Antibodies
High quality antibodies with extensive validation data.
CRTC1 ELISA Kits
Reliable ELISA kits for a wide range of species.
CRTC1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CRTC1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Chicken, Human
Application
WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN746558
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, FACS, ICC
Validations
- (4)
Cat. No.
ABIN6241239
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS, ICC
Validations
- (3)
- (3)
Cat. No.
ABIN969066
Quantity
100 μL
Datasheet
Datasheet
Recommended CRTC1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955105
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Sandwich ELISA
Validations
Cat. No.
ABIN427062
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6203034
Quantity
96 tests
Datasheet
Datasheet
Recommended CRTC1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350404
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7420138
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3091973
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CRTC1 products
: "Stimulation by lithium of the interaction between the transcription factor CREB and its co-activator TORC." in: Bioscience reports, Vol. 29, Issue 2, pp. 77-87, (2009) (PubMed).: "A closer look at Warthin tumors and the t(11;19)." in: Cancer genetics and cytogenetics, Vol. 180, Issue 2, pp. 135-9, (2008) (PubMed).
: "Frequent fusion of the CRTC1 and MAML2 genes in clear cell variants of cutaneous hidradenomas." in: Genes, chromosomes & cancer, Vol. 46, Issue 6, pp. 559-63, (2007) (PubMed).
: "t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway." in: Nature genetics, Vol. 33, Issue 2, pp. 208-13, (2003) (PubMed).
Synonyms and alternative names related to CRTC1
CREB regulated transcription coactivator 1 (CRTC1), CREB regulated transcription coactivator 1 (Crtc1), CREB regulated transcription coactivator 1 (crtc1), CREB regulated transcription coactivator 1b (crtc1b), AI413414, CRTC1, crtc1, fc68c05, MECT1, Mect1, mKIAA0616, pde4cb, R74955, si:ch211-255d18.1, si:ch211-255d18.8, TORC-1, TORC1, WAMTP1, wu:fc68c05Protein level used designations for CRTC1
- CREB-regulated transcription coactivator 1
- mucoepidermoid carcinoma translocated protein 1
- transducer of regulated cAMP response element-binding protein (CREB) 1
- TORC-1
- mucoepidermoid carcinoma translocated 1
- mucoepidermoid carcinoma translocated protein 1 homolog
- transducer of CREB protein 1
- transducer of regulated cAMP response element-binding protein 1
- CREB regulated transcription coactivator 1
- CREB-regulated transcription coactivator 1-like
- CH211-255D18.10
- CH211-255D18.9
- CREB regulated transcription coactivator 1b
- cAMP-specific 3',5'-cyclic phosphodiesterase 4C
- phosphodiesterase 4C, cAMP-specific b
- zfTorc1
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