CRH Products
(Corticotropin Releasing Hormone (CRH))
Categories
Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010].
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Featured CRH Categories
CRH Antibodies
High quality antibodies with extensive validation data.
CRH ELISA Kits
Reliable ELISA kits for a wide range of species.
CRH Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CRH Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7429697
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN739430
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (4)
Cat. No.
ABIN6261032
Quantity
100 μL
Datasheet
Datasheet
Recommended CRH ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
- (4)
Cat. No.
ABIN6574093
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse, Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (9)
Cat. No.
ABIN956064
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6963683
Quantity
96 tests
Datasheet
Datasheet
Recommended CRH Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350331
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350330
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505109
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CRH products
: "Mast-cell-specific receptor mediates alcohol-withdrawal-associated headache in male mice." in: Neuron, (2023) (PubMed).: "Contribution of DNA methylation in chronic stress-induced cardiac remodeling and arrhythmias in mice." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 11, pp. 12240-12252, (2020) (PubMed).
: "Anxiolytic and antioxidant effects of Euterpe oleracea Mart. (açaí) seed extract in adult rat offspring submitted to periodic maternal separation." in: Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme, Vol. 45, Issue 11, pp. 1277-1286, (2020) (PubMed).
: "ACYLOXYACYL HYDROLASE MODULATES DEPRESSIVE-LIKE BEHAVIORS THROUGH ARYL HYDROCARBON RECEPTOR." in: American journal of physiology. Regulatory, integrative and comparative physiology, (2019) (PubMed).
: "Heat stress-induced neuroinflammation and aberration in monoamine levels in hypothalamus are associated with temperature dysregulation." in: Neuroscience, Vol. 358, pp. 79-92, (2018) (PubMed).
: "Colonic Transit Time and Gut Peptides in Adult Patients with Slow and Normal Colonic Transit Constipation." in: BioMed research international, Vol. 2017, pp. 3178263, (2018) (PubMed).
: "Microbiota Modulate Anxiety-Like Behavior and Endocrine Abnormalities in Hypothalamic-Pituitary-Adrenal Axis." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 489, (2018) (PubMed).
: "Activation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 46, Issue 6, pp. 786-793, (2018) (PubMed).
: "Tetramethylpyrazine reverses anxiety-like behaviors in a rat model of post-traumatic stress disorder." in: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, Vol. 22, Issue 5, pp. 525-538, (2018) (PubMed).
: "The depressive-like behaviors of chronic unpredictable mild stress-treated mice, ameliorated by Tibetan medicine Zuotai: involvement in the hypothalamic-pituitary-adrenal (HPA) axis pathway." in: Neuropsychiatric disease and treatment, Vol. 14, pp. 129-141, (2018) (PubMed).
Synonyms and alternative names related to CRH
corticotropin releasing hormone (Crh), corticotropin releasing hormone (CRH), corticotropin releasing hormone b (crhb), corticotropin releasing hormone (crh), corticotropin releasing hormone S homeolog (crh.S), corticotropin releasing hormone L homeolog (crh.L), corticoliberin, CRF, crf, crh, CRH, crh.1-a, crha, crhb, Gm1347, zgc:101864Protein level used designations for CRH
- corticoliberin
- corticotropin releasing factor
- corticotropin-releasing factor
- corticotropin-releasing hormone
- CRF
- corticotropin releasing hormone
- corticotrophin-releasing factor
- corticotropin releasing hormone, gene 1
- corticotropin-releasing factor b
- corticotropin releasing hormone b
- Corticotropin-releasing hormone
- corticotropin releasing hormone a
- corticotropin-releasing factor a
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