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CREM Products

(CAMP Responsive Element Modulator (CREM))

Categories

This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008].

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Featured CREM Categories

CREM Antibodies

High quality antibodies with extensive validation data.

CREM ELISA Kits

Reliable ELISA kits for a wide range of species.

CREM Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CREM Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN560468
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (3)
Cat. No. ABIN653067
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7146628
Quantity 100 μg
Datasheet Datasheet

Recommended CREM ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648011
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5591756
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6202310
Quantity 96 tests
Datasheet Datasheet

Recommended CREM Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350328
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350326
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3133527
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CREM products

Sunahori, Juang, Tsokos: "Methylation status of CpG islands flanking a cAMP response element motif on the protein phosphatase 2Ac alpha promoter determines CREB binding and activity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 3, pp. 1500-8, (2009) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Tenbrock, Juang, Tolnay, Tsokos: "The cyclic adenosine 5'-monophosphate response element modulator suppresses IL-2 production in stimulated T cells by a chromatin-dependent mechanism." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 6, pp. 2971-6, (2003) (PubMed).

Synonyms and alternative names related to CREM

cAMP responsive element modulator (CREM), cAMP responsive element modulator (Crem), CREM, CREM-2, hCREM-2, ICER, Icer, ICERI

Protein level used designations for CREM

  • cAMP responsive element modulator
  • cAMP response element modulator tau
  • ICER protein
  • cAMP-responsive element modulator
  • CREM 2alpha-b protein
  • CREM 2beta-a protein
  • cAMP response element modulator
  • inducible cAMP early repressor ICER
  • cAMP responsive element moderator
  • cAMP-responsive element moderator
  • CRE modulator
  • inducible cyclic AMP early repressor
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