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CPT1A Products

(Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))

Categories

The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured CPT1A Categories

CPT1A Antibodies

High quality antibodies with extensive validation data.

CPT1A ELISA Kits

Reliable ELISA kits for a wide range of species.

CPT1A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CPT1A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IP, IF
Validations
  • (2)
  • (8)
Cat. No. ABIN6138976
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7436006
Quantity 100 μL
Datasheet Datasheet

Application WB, IHC
Validations
  • (3)
  • (7)
Cat. No. ABIN2782010
Quantity 100 μL
Datasheet Datasheet

Recommended CPT1A ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954382
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6975857
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965426
Quantity 96 tests
Datasheet Datasheet

Recommended CPT1A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122154
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350246
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350244
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our CPT1A products

Mørkholt, Trabjerg, Oklinski, Bolther, Kroese, Pritchard, Huijbers, Nieland: "CPT1A plays a key role in the development and treatment of multiple sclerosis and experimental autoimmune encephalomyelitis." in: Scientific reports, Vol. 9, Issue 1, pp. 13299, (2019) (PubMed).

Zhao, Niu, Lin, Zhao, Liu, Song, Xiang, Wang, Yang, Li, Mohammadi, Huang: "Paracrine-endocrine FGF chimeras as potent therapeutics for metabolic diseases." in: EBioMedicine, Vol. 48, pp. 462-477, (2019) (PubMed).

Yang, He, Yao, Tan, Zhu, Li, Guo, Wei: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." in: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).

Ni, He, Dai, Yao, Guo, Wei: "Oroxylin A suppresses the development and growth of colorectal cancer through reprogram of HIF1α-modulated fatty acid metabolism." in: Cell death & disease, Vol. 8, Issue 6, pp. e2865, (2018) (PubMed).

Piemontese, Cerchia, Laghezza, Ziccardi, Sblano, Tortorella, Iacobazzi, Infantino, Convertini, Dal Piaz, Lupo, Colantuoni, Lavecchia, Loiodice: "New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity." in: European journal of medicinal chemistry, Vol. 127, pp. 379-397, (2017) (PubMed).

Shi, Wang, Yang, Xie, Zhu: "IMM-H007, a new therapeutic candidate for nonalcoholic fatty liver disease, improves hepatic steatosis in hamsters fed a high-fat diet." in: FEBS open bio, Vol. 7, Issue 9, pp. 1379-1391, (2017) (PubMed).

Fan, Li, Nie, Yin, Zhao, Chen, Wen Wang: "MiR-30c-5p ameliorates hepatic steatosis in leptin receptor-deficient (db/db) mice via down-regulating FASN." in: Oncotarget, Vol. 8, Issue 8, pp. 13450-13463, (2017) (PubMed).

Convertini, Menga, Andria, Scala, Santarsiero, Castiglione Morelli, Iacobazzi, Infantino: "The contribution of the citrate pathway to oxidative stress in Down syndrome." in: Immunology, Vol. 149, Issue 4, pp. 423-431, (2016) (PubMed).

Patsoukis, Bardhan, Chatterjee, Sari, Liu, Bell, Karoly, Freeman, Petkova, Seth, Li, Boussiotis: "PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation." in: Nature communications, Vol. 6, pp. 6692, (2015) (PubMed).

Kim, Kim, Kim, Om: "Beneficial effects of Allium sativum L. stem extract on lipid metabolism and antioxidant status in obese mice fed a high-fat diet." in: Journal of the science of food and agriculture, Vol. 93, Issue 11, pp. 2749-57, (2014) (PubMed).

Synonyms and alternative names related to CPT1A

carnitine palmitoyltransferase 1A (liver) L homeolog (cpt1a.L), carnitine palmitoyltransferase 1A (CPT1A), carnitine palmitoyltransferase 1A (liver) (cpt1a), carnitine palmitoyltransferase 1A (cpt1a), carnitine palmitoyltransferase 1Aa (liver) (cpt1aa), carnitine palmitoyltransferase 1a, liver (Cpt1a), carnitine palmitoyltransferase 1A (Cpt1a), C730027G07, CPT-Ia, CPT1, Cpt1, CPT1-L, CPTI, L-CPT1, L-CPTI, MGC53498, si:dkey-56p7.8

Protein level used designations for CPT1A

  • carnitine palmitoyltransferase 1A (liver)
  • carnitine O-palmitoyltransferase 1, liver isoform-like
  • CPT I
  • CPTI-L
  • carnitine O-palmitoyltransferase 1, liver isoform
  • carnitine O-palmitoyltransferase I, liver isoform
  • carnitine palmitoyltransferase I, liver
  • carnitine palmitoyl transferase I liver isoform
  • liver type carnitine palmitoyltransferase I
  • mitochondrial carnitine palmitoyltransferase 1A
  • carnitine palmitoyltransferase 1A
  • carnitine palmitoyltransferase I
  • carnitine palmitoyl transferase I isoform
  • CPT1-L
  • L-CPT I
  • carnitine palmitoyltransferase 1, liver
  • Carnitine palmitoyltransferase 1 alpha, liver isoform
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