CPSF6 Products
(Cleavage and Polyadenylation Specific Factor 6, 68kDa (CPSF6))
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The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008].
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Featured CPSF6 Categories
CPSF6 Antibodies
High quality antibodies with extensive validation data.
CPSF6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CPSF6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (2)
- (8)
Cat. No.
ABIN524445
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (7)
Cat. No.
ABIN6138974
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7147925
Quantity
100 μg
Datasheet
Datasheet
Recommended CPSF6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350240
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350242
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2712536
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our CPSF6 products
: "Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo." in: Journal of virology, Vol. 90, Issue 15, pp. 6918-35, (2016) (PubMed).: "Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid." in: eLife, Vol. 3, pp. e04114, (2015) (PubMed).
: "In vivo functions of CPSF6 for HIV-1 as revealed by HIV-1 capsid evolution in HLA-B27-positive subjects." in: PLoS pathogens, Vol. 10, Issue 1, pp. e1003868, (2014) (PubMed).
: "TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm." in: Retrovirology, Vol. 10, pp. 20, (2013) (PubMed).
: "The ability of TNPO3-depleted cells to inhibit HIV-1 infection requires CPSF6." in: Retrovirology, Vol. 10, pp. 46, (2013) (PubMed).
: "Evidence that cleavage factor Im is a heterotetrameric protein complex controlling alternative polyadenylation." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 15, Issue 9, pp. 1003-13, (2010) (PubMed).
: "Flexible use of nuclear import pathways by HIV-1." in: Cell host & microbe, Vol. 7, Issue 3, pp. 221-33, (2010) (PubMed).
: "Novel snail1 target proteins in human colon cancer identified by proteomic analysis." in: PLoS ONE, Vol. 5, Issue 4, pp. e10221, (2010) (PubMed).
: "Mammalian pre-mRNA 3' end processing factor CF I m 68 functions in mRNA export." in: Molecular biology of the cell, Vol. 20, Issue 24, pp. 5211-23, (2009) (PubMed).
: "Shifted Transversal Design smart-pooling for high coverage interactome mapping." in: Genome research, Vol. 19, Issue 7, pp. 1262-9, (2009) (PubMed).
Synonyms and alternative names related to CPSF6
cleavage and polyadenylation specific factor 6 (CPSF6), cleavage and polyadenylation specific factor 6 S homeolog (cpsf6.S), cleavage and polyadenylation specific factor 6 (cpsf6), cleavage and polyadenylation specific factor 6 (Cpsf6), 4733401N12Rik, AI256641, CFIM, CFIM68, CPSF6, HPBRII-4, HPBRII-7, wu:fa22f12, zgc:85819Protein level used designations for CPSF6
- cleavage and polyadenylation specific factor 6, 68kDa
- cleavage and polyadenylation specificity factor subunit 6
- cleavage and polyadenylation specific factor 6, 68 kD subunit
- CPSF 68 kDa subunit
- cleavage and polyadenylation specificity factor 68 kDa subunit
- cleavage factor Im complex 68 kDa subunit
- pre-mRNA cleavage factor I, 68kD subunit
- pre-mRNA cleavage factor Im (68kD)
- pre-mRNA cleavage factor Im 68 kDa subunit
- protein HPBRII-4/7
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