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CPSF2 Products

(Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2))

Categories

Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing (By similarity).

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Featured CPSF2 Categories

CPSF2 Antibodies

High quality antibodies with extensive validation data.

CPSF2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CPSF2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN527000
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN526998
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN6138966
Quantity 100 μL
Datasheet Datasheet

Recommended CPSF2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350229
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350231
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3091911
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CPSF2 products

Shi, Zhang, Wu, He, Wang, Yin, Tian, Li, Cheng: "ALYREF mainly binds to the 5' and the 3' regions of the mRNA in vivo." in: Nucleic acids research, Vol. 45, Issue 16, pp. 9640-9653, (2017) (PubMed).

Tran, Saran, Williamson, Pierce, Dittrich-Breiholz, Wiehlmann, Koch, Whetton, Tamura: "THOC5 controls 3'end-processing of immediate early genes via interaction with polyadenylation specific factor 100 (CPSF100)." in: Nucleic acids research, Vol. 42, Issue 19, pp. 12249-60, (2014) (PubMed).

Sagawa, Ibrahim, Morrison, Wilusz, Wilusz: "Nucleophosmin deposition during mRNA 3' end processing influences poly(A) tail length." in: The EMBO journal, Vol. 30, Issue 19, pp. 3994-4005, (2011) (PubMed).

Kolev, Yario, Benson, Steitz: "Conserved motifs in both CPSF73 and CPSF100 are required to assemble the active endonuclease for histone mRNA 3'-end maturation." in: EMBO reports, Vol. 9, Issue 10, pp. 1013-8, (2008) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, (2004) (PubMed).

Hodgman, Tay, Mendez, Richter: "CPEB phosphorylation and cytoplasmic polyadenylation are catalyzed by the kinase IAK1/Eg2 in maturing mouse oocytes." in: Development (Cambridge, England), Vol. 128, Issue 14, pp. 2815-22, (2001) (PubMed).

de Vries, Rüegsegger, Hübner, Friedlein, Langen, Keller: "Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors." in: The EMBO journal, Vol. 19, Issue 21, pp. 5895-904, (2000) (PubMed).

Synonyms and alternative names related to CPSF2

cleavage and polyadenylation specific factor 2 (CPSF2), cleavage and polyadenylation specific factor 2 (Cpsf2), cleavage and polyadenylation specific factor 2 (cpsf2), cleavage and polyadenylation specific factor 2 (PAAG_07931), cleavage and polyadenylation specific factor 2 S homeolog (cpsf2.S), cleavage and polyadenylation specificity factor subunit 2 (LOC582050), cleavage and polyadenylation specificity factor subunit 2 (LOC100157277), cleavage and polyadenylation specificity factor subunit 2 (LOC100179344), 100kDa, 2610024B04Rik, AI662483, Cpsf, cpsf2-A, CPSF100, MCPSF, mKIAA1367, zgc:92484

Protein level used designations for CPSF2

  • CPSF 100 kDa subunit
  • CPSF 100kDa subunit
  • cleavage and polyadenylation specificity factor 100 kDa subunit
  • cleavage and polyadenylation specificity factor subunit 2
  • cleavage and polyadenylation specific factor 2, 100kD subunit
  • cleavage and polyadenylation specific factor 2
  • cleavage and polyadenylation specific factor 2, 100kDa
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