COX4I2 Products
(Cytochrome C Oxidase Subunit IV Isoform 2 (Lung) (COX4I2))
Categories
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq, Jul 2008].
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Featured COX4I2 Categories
COX4I2 Antibodies
High quality antibodies with extensive validation data.
COX4I2 ELISA Kits
Reliable ELISA kits for a wide range of species.
COX4I2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended COX4I2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP, IHC (p)
Validations
- (6)
- (6)
Cat. No.
ABIN566588
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6260988
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF, IHC, IC
Validations
- (3)
Cat. No.
ABIN7303608
Quantity
100 μL
Datasheet
Datasheet
Recommended COX4I2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955220
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Sandwich ELISA
Validations
Cat. No.
ABIN418978
Quantity
96 tests
Datasheet
Datasheet
Recommended COX4I2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122573
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350123
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350121
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our COX4I2 products
: "Control of human energy expenditure by cytochrome c oxidase subunit IV-2." in: American journal of physiology. Cell physiology, Vol. 311, Issue 3, pp. C452-61, (2016) (PubMed).: "Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2." in: Nucleic acids research, Vol. 41, Issue 4, pp. 2255-66, (2013) (PubMed).
: "Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology. ..." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 9, pp. 3916-30, (2012) (PubMed).
: "Sex- and brain region-specific role of cytochrome c oxidase in 1-methyl-4-phenylpyridinium-mediated astrocyte vulnerability." in: Journal of neuroscience research, Vol. 89, Issue 12, pp. 2068-82, (2011) (PubMed).
: "Brain region specificity of 3-nitropropionic acid-induced vulnerability of neurons involves cytochrome c oxidase." in: Neurochemistry international, Vol. 57, Issue 3, pp. 297-305, (2010) (PubMed).
: "Brain region-specific vulnerability of astrocytes in response to 3-nitropropionic acid is mediated by cytochrome c oxidase isoform expression." in: Cell and tissue research, Vol. 341, Issue 1, pp. 83-93, (2010) (PubMed).
Synonyms and alternative names related to COX4I2
cytochrome c oxidase subunit 4I2 (COX4I2), cytochrome c oxidase subunit IV isoform 2 (cox4i2), cytochrome c oxidase subunit 4I2 S homeolog (cox4i2.S), cytochrome c oxidase subunit 4I2 (cox4i2), cytochrome c oxidase subunit IV isoform 2 (lung) (COX4I2), cytochrome c oxidase subunit 4I2 (Cox4i2), cytochrome c oxidase subunit 4i2 (Cox4i2), COX4, COX4-2, cox4-2, COX4B, cox4b, Cox4b, COX4L2, cox4l2, COXIV-2, coxiv-2, CoxIV-2, dJ857M17.2, zgc:73355Protein level used designations for COX4I2
- COX IV-2
- cytochrome c oxidase subunit 4 isoform 2, mitochondrial
- cytochrome c oxidase subunit IV-like 2
- Cox4-2
- Cox IV-2
- cytochrome c oxidase, subunit IVb
- cytochrome c oxidase, subunit 4b
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