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CORT Products

(Cortistatin (CORT))
This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739. [provided by RefSeq, Nov 2010].

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Featured CORT Categories

CORT Antibodies

High quality antibodies with extensive validation data.

CORT ELISA Kits

Reliable ELISA kits for a wide range of species.

CORT Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CORT Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN1989507
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN929265
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA
Validations
Cat. No. ABIN7096703
Quantity 100 μL
Datasheet Datasheet

Recommended CORT ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
Cat. No. ABIN6955094
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1028447
Quantity 96 tests
Datasheet Datasheet
Reactivity Dog
Analytical Method Quantitative
Validations
Cat. No. ABIN364652
Quantity 96 tests
Datasheet Datasheet

Recommended CORT Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350095
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7396271
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN3143319
Quantity 2 mg
Datasheet Datasheet

Latest Publications for our CORT products

Akbas, Koltan, Koyuncu, Artunc Ulkumen, Taneli, Ozdemir: "Decreased maternal serum cortistatin levels in pregnancies with gestational diabetes mellitus." in: The journal of maternal-fetal & neonatal medicine, Vol. 33, Issue 7, pp. 1239-1244, (2020) (PubMed).

Xu, Lang, Li, Guo, Wang, Yang, Lian: "Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure." in: Biomolecules, Vol. 9, Issue 9, (2020) (PubMed).

Lee, Shim, Lee, Hahm: "Tetramethylpyrazine reverses anxiety-like behaviors in a rat model of post-traumatic stress disorder." in: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, Vol. 22, Issue 5, pp. 525-538, (2018) (PubMed).

Zhang, Li, Zhu, Wang, Lv, Xiong: "Etomidate increases mortality in septic rats through inhibition of nuclear factor kappa-B rather than by causing adrenal insufficiency." in: The Journal of surgical research, Vol. 193, Issue 1, pp. 399-406, (2014) (PubMed).

DeVries, Holbrook, Winters, Jawor: "Non-breeding gonadal testosterone production of male and female northern cardinals (Cardinalis cardinalis) following GnRH challenge." in: General and comparative endocrinology, Vol. 174, Issue 3, pp. 370-8, (2011) (PubMed).

Greene, Bahn, Masson, Rabbitts: "The T-cell oncogenic protein HOX11 activates Aldh1 expression in NIH 3T3 cells but represses its expression in mouse spleen development." in: Molecular and cellular biology, Vol. 18, Issue 12, pp. 7030-7, (1998) (PubMed).

Kathmann, Lipsky: "Cloning of a cDNA encoding a constitutively expressed rat liver cytosolic aldehyde dehydrogenase." in: Biochemical and biophysical research communications, Vol. 236, Issue 2, pp. 527-31, (1997) (PubMed).

Synonyms and alternative names related to CORT

cortistatin (CORT), cortistatin (Cort), CST, CST-14, CST-17, CST-29, PCST

Protein level used designations for CORT

  • cortistatin-14
  • cortistatin-17
  • cortistatin-29
  • prepro-cortistatin
  • preprocortistatin
  • Preprocortistatin
  • cortistatin
  • cortistatin preproprotein-like
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