COPS8 Products
(COP9 Signalosome Subunit 8 (COPS8))
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The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
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Featured COPS8 Categories
COPS8 Antibodies
High quality antibodies with extensive validation data.
COPS8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended COPS8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN524327
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN6138889
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN524324
Quantity
50 μL
Datasheet
Datasheet
Recommended COPS8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6213819
Quantity
96 tests
Datasheet
Datasheet
Recommended COPS8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN2752761
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN667600
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2128659
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our COPS8 products
: "The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain." in: PLoS ONE, Vol. 7, Issue 8, pp. e43980, (2012) (PubMed).: "The COP9 signalosome." in: Annual review of cell and developmental biology, Vol. 19, pp. 261-86, (2003) (PubMed).
: "Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome." in: The EMBO journal, Vol. 22, Issue 6, pp. 1302-12, (2003) (PubMed).
: "The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage." in: Cell, Vol. 113, Issue 3, pp. 357-67, (2003) (PubMed).
: "The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis." in: Journal of cell science, Vol. 115, Issue Pt 3, pp. 467-73, (2002) (PubMed).
Synonyms and alternative names related to COPS8
COP9 signalosome subunit 8 (COPS8), COP9 signalosome subunit 8 (Cops8), COP9 signalosome subunit 8 (cops8), COP9 signalosome subunit 8 S homeolog (cops8.S), COP9 signalosome complex subunit 8 (CSN8), COP9 signalosome complex subunit 8 (csn8), COP9 signalosome subunit 8 L homeolog (cops8.L), COP9 signalosome, subunit CSN8 (COP9), COP9 signalosome subunit 8 (CSN8), 9430009J09Rik, AA408242, CG13383, CG33297, CG42522, CH8, CONSTITUTIVE PHOTOMORPHOGENIC 9, COP9, COP9 SIGNALOSOME SUBUNIT 8, cops8, CSN8, csn8, Csn8, Dch8, DDBDRAFT_0167123, DDBDRAFT_0233107, DDB_0167123, DDB_0233107, DL3095C, Dmel\\CG42522, Dmel_CG13383, EMB143, EMBRYO DEFECTIVE 143, FCAALL.131, FUS7, FUSCA 7, FUSCA PROTEIN FUS7, l(2)SH2 1829, l(2)SH1829, MGC76051, MGC80215, MGC86182, SGN8, Sgn8, zgc:56319, zgc:86840Protein level used designations for COPS8
- COP9 constitutive photomorphogenic homolog subunit 8
- COP9 homolog
- COP9 signalosome complex subunit 8
- JAB1-containing signalosome subunit 8
- hCOP9
- signalosome subunit 8
- COP9 (constitutive photomorphogenic) homolog, subunit 8
- SGN8
- COP9 signalosome subunit 8
- MGC80215 protein
- COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
- CG42522-PB
- CSN8-PB
- Cop9 signalosome subunit 8
- drosophila COP9 signalosome homolog 8
- lethal (2) SH1829
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