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COPS6 Products

(COP9 Signalosome Complex Subunit 6 (COPS6))

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The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq, Jul 2008].

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Featured COPS6 Categories

COPS6 Antibodies

High quality antibodies with extensive validation data.

COPS6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended COPS6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN1491601
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN1491602
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN6138885
Quantity 100 μL
Datasheet Datasheet

Recommended COPS6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350063
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350061
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7420297
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our COPS6 products

Scimeca, Piccirilli, Mastrangeli, Rao, Feola, Orlandi, Gasbarra, Bonanno, Tarantino: "Bone Morphogenetic Proteins and myostatin pathways: key mediator of human sarcopenia." in: Journal of translational medicine, Vol. 15, Issue 1, pp. 34, (2017) (PubMed).

Pick, Golan, Zimbler, Guo, Sharaby, Tsuge, Hofmann, Wei: "The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain." in: PLoS ONE, Vol. 7, Issue 8, pp. e43980, (2012) (PubMed).

Synonyms and alternative names related to COPS6

COP9 signalosome subunit 6 (COPS6), COP9 signalosome subunit 6 (Cops6), COP9 signalosome subunit 6 (CSN6), COP9 signalosome subunit 6 (cops6), COP-9 SigNalosome subunit (csn-6), CG6932, CH6, Csn6, CSN6, Dch6, Dmel\\CG6932, MOV34-34KD, Sgn3, VIP/MOV34, zgc:112075

Protein level used designations for COPS6

  • COP9 (constitutive photomorphogenic) homolog, subunit 6
  • COP9 constitutive photomorphogenic homolog subunit 6
  • COP9 signalosome complex subunit 6
  • CG6932-PA
  • CSN6-PA
  • drosophila COP9 signalosome homolog 6
  • COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)
  • COP9 (constitutive photomorphogenic), subunit 6
  • COP9 complex S6
  • JAB1-containing signalosome subunit 6
  • SGN6
  • signalosome subunit 6
  • COP9 signalosome subunit 6
  • COP9 subunit 6 (MOV34 homolog, 34 kD)
  • H_NH0506M12.12
  • MOV34 homolog, 34 kD
  • hVIP
  • vpr-interacting protein
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