COPRS Products
(Coordinator of PRMT5, Differentiation Stimulator (COPRS))
Categories
Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression (By similarity).
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Featured COPRS Categories
COPRS ELISA Kits
Reliable ELISA kits for a wide range of species.
COPRS Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended COPRS ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955067
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5653315
Quantity
96 tests
Datasheet
Datasheet
Recommended COPRS Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7410052
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3128232
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN6378769
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our COPRS products
: "KSHV encoded ORF59 modulates histone arginine methylation of the viral genome to promote viral reactivation." in: PLoS pathogens, Vol. 13, Issue 7, pp. e1006482, (2017) (PubMed).: "Myc and Omomyc functionally associate with the Protein Arginine Methyltransferase 5 (PRMT5) in glioblastoma cells." in: Scientific reports, Vol. 5, pp. 15494, (2015) (PubMed).
Synonyms and alternative names related to COPRS
coordinator of PRMT5 and differentiation stimulator (COPRS), coordinator of PRMT5, differentiation stimulator (Coprs), 1700029I03Rik, 2410022L05Rik, AA409325, AI256813, C17orf79, C19H17orf79, C85432, COPR5, Copr5, HSA272196, TTP1Protein level used designations for COPRS
- cooperator of PRMT5
- coordinator of PRMT5 and differentiation stimulator
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