Complement C5b Products
(Complement C5 beta Chain (C5b))
Categories
The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis. [provided by RefSeq, Jul 2008].
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Featured Complement C5b Categories
Complement C5b ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended Complement C5b Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC (fro)
Validations
Cat. No.
ABIN284013
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Cow, Goat, Human, Pig, Primate
Application
ELISA, WB, IHC
Validations
Cat. No.
ABIN5954788
Quantity
50 μg
Datasheet
Datasheet
Recommended Complement C5b ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966049
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962122
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Guinea Pig
Analytical Method
Quantitative
Validations
- (1)
Cat. No.
ABIN1052365
Quantity
96 tests
Datasheet
Datasheet
Synonyms and alternative names related to Complement C5b
complement C5 (C5), C5a, C5b, CPAMD4Protein level used designations for Complement C5b
- C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4
- C5a anaphylatoxin
- anaphylatoxin C5a analog
- complement C5
- prepro-C5
Did you look for something else?
- Complement C5 Convertase
- Complement C4d
- Complement C4c
- Complement C4
- Complement C3d
- Complement C3c
- Complement C3b
- Complement C3 Convertase
- Complement C2
- Complement C1
- COMP
- COMMD9
- COMMD8
- COMMD7
- COMMD6
- COMMD5
- COMMD4
- COMMD3
- COMMD2
- COMMD10
- Complement C8
- Complement Component C9b
- Complement Factor B
- Complement Factor Bb
- Complement Factor H
- Complement Factor I
- Complexin 1
- Complexin 4
- Component of Type IV Secretion System
- COMT1
- COMTD1
- Concanavalin A
- Cone-Rod Homeobox
- Connexin
- Connexin 31
- Connexin 43/GJA1
- Contactin 1
- Contactin 4
- Contactin 5
- Contactin 6
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