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COMP Proteins

(Cartilage Oligomeric Matrix Protein (COMP))
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2008].
COMP Protein (C-Term) COMP Protein (C-Term) COMP Protein (C-Term) (ABIN1047991)

COMP Origin: Rat Recombinant > 95 % (SDS-PAGE)

COMP Protein (AA 22-240) (GST-His-Tag) (ABIN7505321)

COMP Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.

COMP Protein (His tag) (ABIN7534406)

COMP Origin: Human Host: HEK-293 Cells Recombinant > 90 % by SDS-PAGE.

COMP Proteins by Origin

Find COMP Proteins for a variety of species such as anti-Human COMP, anti-Rat COMP, anti-Mouse COMP. The species listed below are among those available. Click on a link to go to the corresponding products.

COMP Proteins by Source

Here you will find COMP Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

COMP Proteins by Protein Type

Here you can find COMP Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

COMP Proteins by Application

Find COMP Proteins validated for a specific application such as SDS, WB, Imm, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

COMP Proteins by Biological Activity

Find COMP Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular COMP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Source
Validations
  • (1)
  • (1)
Cat. No. ABIN1047991
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505321
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7534406
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393391
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7421479
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393394
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7402583
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7402586
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393397
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7403273
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7317991
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2180897
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3008640
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2712452
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN1061972
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our COMP Proteins

Wang, Chen, Xiang, Wu, Tang, Ma, Zhang: "ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas." in: FEBS open bio, Vol. 10, Issue 9, pp. 1856-1867, (2020) (PubMed).

Spitznagel, Nitsche, Paulsson, Maurer, Zaucke: "Characterization of a pseudoachondroplasia-associated mutation (His587-->Arg) in the C-terminal, collagen-binding domain of cartilage oligomeric matrix protein (COMP)." in: The Biochemical journal, Vol. 377, Issue Pt 2, pp. 479-87, (2004) (PubMed).

Aliases for COMP Proteins

cartilage oligomeric matrix protein (COMP) Proteins
cartilage oligomeric matrix protein (sce3551) Proteins
cartilage oligomeric matrix protein (CJA_1292) Proteins
cartilage oligomeric matrix protein (Comp) Proteins
COMP Proteins
EDM1 Proteins
EPD1 Proteins
MED Proteins
PSACH Proteins
THBS5 Proteins
TSP5 Proteins
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