COL6a3 Products
(Collagen, Type VI, alpha 3 (COL6a3))
Categories
This gene encodes the alpha-3 chain, one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The alpha-3 chain of type VI collagen is much larger than the alpha-1 and -2 chains. This difference in size is largely due to an increase in the number of subdomains, similar to von Willebrand Factor type A domains, that are found in the amino terminal globular domain of all the alpha chains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in the type VI collagen genes are associated with Bethlem myopathy, a rare autosomal dominant proximal myopathy with early childhood onset. Mutations in this gene are also a cause of Ullrich congenital muscular dystrophy, also referred to as Ullrich scleroatonic muscular dystrophy, an autosomal recessive congenital myopathy that is more severe than Bethlem myopathy. Multiple transcript variants have been identified, but the full-length nature of only some of these variants has been described. [provided by RefSeq, Jun 2009].
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Featured COL6a3 Categories
COL6a3 Antibodies
High quality antibodies with extensive validation data.
COL6a3 ELISA Kits
Reliable ELISA kits for a wide range of species.
COL6a3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended COL6a3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, WB, IP, ICC
Validations
- (7)
Cat. No.
ABIN7434719
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
IHC, WB, IP, ICC
Validations
- (3)
Cat. No.
ABIN7443926
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7183368
Quantity
100 μL
Datasheet
Datasheet
Recommended COL6a3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6954957
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962139
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951494
Quantity
96 tests
Datasheet
Datasheet
Recommended COL6a3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7395962
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7417534
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
Cat. No.
ABIN7317154
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our COL6a3 products
: "Isolation and characterisation of a novel trophoblast side-population from first trimester placentae." in: Reproduction (Cambridge, England), Vol. 150, Issue 5, pp. 449-62, (2015) (PubMed).: "Clinical significance of serum COL6A3 in pancreatic ductal adenocarcinoma." in: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, Vol. 18, Issue 1, pp. 7-15, (2014) (PubMed).
: "COL6A3 is regulated by leptin in human adipose tissue and reduced in obesity." in: Endocrinology, Vol. 156, Issue 1, pp. 134-46, (2014) (PubMed).
Synonyms and alternative names related to COL6a3
collagen type VI alpha 3 chain (COL6A3), collagen, type VI, alpha 3 (col6a3), collagen, type VI, alpha 3 (Col6a3), collagen type VI alpha 3 chain (Col6a3), AI507288, Col6a-3, COL6A3, wu:fb06e12, wu:fs74g09Protein level used designations for COL6a3
- collagen alpha-3(VI) chain
- type VI collagen alpha 3 chain
- alpha 3 type VI collagen
- collagen, type VI, alpha 3
- collagen alpha-3(VI) chain-like
- collagen alpha 3 chain type VI
- collagen alpha3(VI)
- procollagen, type VI, alpha 3
- type VI collagen alpha 3 subunit
- collagen VI, alpha-3 polypeptide
- alpha-3 collagen type VI
- collagen type VI alpha 3
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