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COL3 Products

(Collagen, Type III (COL3))
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. [provided by RefSeq, Jul 2008].

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Featured COL3 Categories

COL3 Antibodies

High quality antibodies with extensive validation data.

COL3 ELISA Kits

Reliable ELISA kits for a wide range of species.

COL3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended COL3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Human, Mammalian
Application WB, ELISA, IHC, IP
Validations
  • (5)
  • (5)
  • (1)
Cat. No. ABIN5596830
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Human, Mouse, Rabbit, Rat
Application WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p)
Validations
  • (11)
  • (5)
Cat. No. ABIN669981
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (5)
Cat. No. ABIN7266459
Quantity 100 μL
Datasheet Datasheet

Recommended COL3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (10)
  • (1)
Cat. No. ABIN6954932
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6963127
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954933
Quantity 96 tests
Datasheet Datasheet

Recommended COL3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Human
Validations
  • (1)
Cat. No. ABIN5624594
Quantity 500 μg
Datasheet Datasheet
Reactivity Cow
Source Cow
Validations
Cat. No. ABIN376678
Quantity 0.5 mg
Datasheet Datasheet
Reactivity Human
Source Human
Validations
Cat. No. ABIN376677
Quantity 0.5 mg
Datasheet Datasheet

Latest Publications for our COL3 products

Yang, Li, Guo, Pan, Yan, Chen: "Hirudo Lyophilized Powder Ameliorates Renal Injury in Diabetic Rats by Suppressing Oxidative Stress and Inflammation." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2021, pp. 6657673, (2021) (PubMed).

Jiao, Bai, Yin, Liu, Sun, Su, Zeng, Wen: "Therapeutic Effects of an Inhibitor of Thioredoxin Reductase on Liver Fibrosis by Inhibiting the Transforming Growth Factor-β1/Smads Pathway." in: Frontiers in molecular biosciences, Vol. 8, pp. 690170, (2021) (PubMed).

Jackson, Kopecki, Anderson, Cowin: "Increasing the level of cytoskeletal protein Flightless I reduces adhesion formation in a murine digital flexor tendon model." in: Journal of orthopaedic surgery and research, Vol. 15, Issue 1, pp. 362, (2020) (PubMed).

Fernandes, Reilly, Schrock, Hocking, Oakes, Fowell: "CD4+ T Cell Interstitial Migration Controlled by Fibronectin in the Inflamed Skin." in: Frontiers in immunology, Vol. 11, pp. 1501, (2020) (PubMed).

Sembach, Fink, Johansen, Boland, Secher, Thrane, Nielsen, Fosgerau, Vrang, Jelsing, Pedersen, Østergaard: "Impact of sex on diabetic nephropathy and the renal transcriptome in UNx db/db C57BLKS mice." in: Physiological reports, Vol. 7, Issue 24, pp. e14333, (2020) (PubMed).

Becker, OConnell, Vo, Cain, Tampe, Bizarro, Sugimoto, McGow, Asara, Lovisa, McAndrews, Zielinski, Lorenzi, Zeisberg, Raza, LeBleu, Kalluri: "Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer." in: Cell reports, Vol. 31, Issue 9, pp. 107701, (2020) (PubMed).

Buhl, Djudjaj, Klinkhammer, Ermert, Puelles, Lindenmeyer, Cohen, He, Borkham-Kamphorst, Weiskirchen, Denecke, Trairatphisan, Saez-Rodriguez, Huber, Olson, Floege, Boor: "Dysregulated mesenchymal PDGFR-β drives kidney fibrosis." in: EMBO molecular medicine, Vol. 12, Issue 3, pp. e11021, (2020) (PubMed).

Dobie, Wilson-Kanamori, Henderson, Smith, Matchett, Portman, Wallenborg, Picelli, Zagorska, Pendem, Hudson, Wu, Budas, Breckenridge, Harrison, Mole, Wigmore, Ramachandran, Ponting, Teichmann, Marioni et al.: "Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis. ..." in: Cell reports, Vol. 29, Issue 7, pp. 1832-1847.e8, (2020) (PubMed).

Hara-Saito, Kato, Saito, Shiomi, Uenoyama, Takagi, Izumi: "Distinct differences in hypoxic responses between human oral mucosa and skin fibroblasts in a 3D collagen matrix." in: In vitro cellular & developmental biology. Animal, Vol. 56, Issue 6, pp. 452-479, (2020) (PubMed).

Wang, Liu, Liang, Yang, Liu, Li, Guo, Wang, Liu, Chen: "Effects of Secreted frizzled-related protein 1 on inhibiting cardiac remodeling." in: European review for medical and pharmacological sciences, Vol. 24, Issue 11, pp. 6270-6278, (2020) (PubMed).

Synonyms and alternative names related to COL3

coagulation factor II, thrombin (F2), coagulation factor II (F2), Cf-2, Cf2, FII, prothrombin, PT, RPRGL2, THPH1, thrombin

Protein level used designations for COL3

  • prepro-coagulation factor II
  • prothrombin
  • prothrombin B-chain
  • serine protease
  • coagulation factor 2
  • thrombin
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