COL2A1 Products
(Collagen, Type II, alpha 1 (COL2A1))
Categories
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008].
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Featured COL2A1 Categories
COL2A1 Antibodies
High quality antibodies with extensive validation data.
COL2A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
COL2A1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended COL2A1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7438682
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF
Validations
- (5)
Cat. No.
ABIN7202718
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN3015516
Quantity
100 μL
Datasheet
Datasheet
Recommended COL2A1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6963494
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965939
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965940
Quantity
96 tests
Datasheet
Datasheet
Recommended COL2A1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349963
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505165
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397267
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our COL2A1 products
: "Moderate Fluid Shear Stress Regulates Heme Oxygenase-1 Expression to Promote Autophagy and ECM Homeostasis in the Nucleus Pulposus Cells." in: Frontiers in cell and developmental biology, Vol. 8, pp. 127, (2020) (PubMed).: "Oestrogen and parathyroid hormone alleviate lumbar intervertebral disc degeneration in ovariectomized rats and enhance Wnt/β-catenin pathway activity." in: Scientific reports, Vol. 6, pp. 27521, (2018) (PubMed).
: "TGF-β1/Smad3 Signaling Pathway Mediates T-2 Toxin-Induced Decrease of Type II Collagen in Cultured Rat Chondrocytes." in: Toxins, Vol. 9, Issue 11, (2018) (PubMed).
: "Establishment of rat ankle post-traumatic osteoarthritis model induced by malleolus fracture." in: BMC musculoskeletal disorders, Vol. 18, Issue 1, pp. 464, (2018) (PubMed).
: "A Human Chondrocyte-Derived In Vitro Model of Alcohol-Induced and Steroid-Induced Femoral Head Necrosis." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 539-547, (2018) (PubMed).
: "Nano-hydroxyapatite/collagen film as a favorable substrate to maintain the phenotype and promote the growth of chondrocytes cultured in vitro." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 2150-2158, (2018) (PubMed).
: "Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 8985623, (2017) (PubMed).
: "Protective effects of baicalin on rabbit articular chondrocytes in vitro." in: Experimental and therapeutic medicine, Vol. 13, Issue 4, pp. 1267-1274, (2017) (PubMed).
: "Effect of NGF From Venom of Chinese Cobra (Naja Atra)on Chondrocytes Proliferation and Metabolism In Vitro." in: Journal of cellular biochemistry, (2017) (PubMed).
: "MiR-351 negatively regulates osteoblast differentiation of MSCs induced by (+)-cholesten-3-one through targeting VDR." in: American journal of translational research, Vol. 9, Issue 11, pp. 4963-4973, (2017) (PubMed).
Synonyms and alternative names related to COL2A1
collagen type II alpha 1 chain (COL2A1), collagen, type II, alpha 1 (Col2a1), collagen type II alpha 1 chain (Col2a1), collagen, type II, alpha 1 (col2a1), collagen, type II, alpha 1 L homeolog (col2a1.L), collagen, type II, alpha 1 S homeolog (col2a1.S), collagen, type II, alpha 1a (col2a1a), ANFH, AOM, CB11, CG2A1A, Col2, Col2a, Col2a-1, col2a1, col2a1a, COL11A3, coll2a1, COLLII, Del1, Dmm, fb38c06, fc10c01, Lpk, M100856, Rgsc856, SEDC, wu:fb38c06, wu:fc10c01Protein level used designations for COL2A1
- alpha-1 type II collagen
- cartilage collagen
- chondrocalcin
- collagen II, alpha-1 polypeptide
- collagen alpha-1(II) chain
- collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital)
- type II collagen
- collagen type IIA
- pro alpha1 type II collagen
- disproportionate micromelia
- procollagen, type II, alpha 1
- Procollagen II alpha 1
- collagen type II (Col2A1) gene, enhancer region
- alpha 1 type II procollagen
- alpha 1 type IIA collagen
- procollagen alpha 1(II)
- type II collagen alpha1
- alpha-1 type II' collagen
- cyanogen bromide
- pro-alpha 1(II)
- collagen, type II, alpha 1
- collagen alpha-1(II) chain-like
- collagen type II
- collagen type II, alpha 1
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