COL25A1 Products
(Collagen, Type XXV, alpha 1 (COL25A1))
Categories
This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
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Featured COL25A1 Categories
COL25A1 Antibodies
High quality antibodies with extensive validation data.
COL25A1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended COL25A1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6257062
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN949736
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN529727
Quantity
100 μg
Datasheet
Datasheet
Recommended COL25A1 Proteins
Latest Publications for our COL25A1 products
: "Collagen XXIII: a potential biomarker for the detection of primary and recurrent non-small cell lung cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1362-72, (2010) (PubMed).Synonyms and alternative names related to COL25A1
collagen type XXV alpha 1 chain (COL25A1), collagen, type XXV, alpha 1 (COL25A1), collagen type XXV alpha 1 chain (col25a1), collagen, type XXV, alpha 1 (Col25a1), collagen type XXV alpha 1 chain (Col25a1), 2700062B08Rik, AMY, CLAC, CLAC-P, CLACP, COL25A1Protein level used designations for COL25A1
- collagen, type XXV, alpha 1
- collagen, type XXV, alpha 1-like
- collagen alpha-1(XXV) chain-like
- alzheimer disease amyloid-associated protein
- collagen alpha-1(XXV) chain
- collagen-like Alzheimer amyloid plaque component
- collagenous Alzheimer amyloid plaque component
- procollagen, type XXV, alpha 1
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